Urinary bladder cancerCSE1LPrognosisTumor markersUrothelial carcinomasPrognosis of urinary bladder urothelial carcinomas may be challenging; many tumors with similar histopathologic features show significantly different clinical outcomes. CSE1L, the chromosome segregation 1-like protein, is both a cytoplasmic ...
The frequent downregulation of CBX7 predicts poor prognosis in UBC patients To explore the potential prognostic value of different CBX members in UBC patients, we first surveyed the expression of CBXs between tumor and normal tissues in TCGA dataset. As shown in Fig.1a, among all eight CBX fam...
diagnostic and prognosis factorsimmunohistochemical markersurinary bladder cancerOn the basis of surgical and biopsy material 106 patients with diseases of urinary bladder have been under study. They received treatment at Scientific Research Institute of Fundamental and Clinical Uronephrology of Saratov State...
bladder cancerimmune checkpoint inhibitorimmunotherapysmall cell carcinoma of urinary bladderurothelial carcinomaIntroduction Small cell carcinoma of urinary bladder is rare and has an aggressive malignant behavior and poor prognosis. Advanced bladder cancers are treated with immune checkpoint inhibitors, however...
relapse. Those features were further integrated into a Random Forest-based model evaluating the risk of relapse for BC patients. Performance of the model was assessed in the test cohort, showing high significance in BC relapse prognosis [HR = 5.76, p-value = 0.0001, c-index = ...
Bladder cancer's staging, treatment and prognosis depend on how deeply it has invaded urinary bladder [3]. Fortunately, about 80% of patients with non-muscle invasive disease can be successfully treated using the surgery. Historically, two-thirds of patients have tumour recurrence within 5 years....
Bladder cancer is a common malignancy with high recurrence rate. Early diagnosis and recurrence surveillance are pivotal to patients’ outcomes, which require novel minimal-invasive diagnostic tools. The urinary microbiome is associated with bladder canc
Recent findings suggest that human microbiome can influence the development of cancer, but the role of microorganisms in bladder cancer pathogenesis has not been explored yet. The aim of this study was to characterize and compare the urinary microbiome o
and Importance: Liver, lung, bone and brain are usual sites for breast cancer metastases. However, colorectal, prostate and cervical tumors may directly invade the urinary bladder (UB), but hematogenous spread from distant organs like the breast, is extremely rare and may indicate poor prognosis....
In that study, including 80 bladder cancer cases (all stages represented), this PTEN/PI3K-gene signature was correlated to poorer prognosis. Our results, at the STMN1 protein level, demonstrating that high STMN1 levels are associated with shorter OS and DSS, in a way, validate the results ...