(I) as uricosuric agents. (where R is H, alkyl, alkenyl, haloalkyl, aralkyl, cycloalkyl, cycloalkylalkyl, alkoxyalkyl, alkanoyloxyalkyl, haloalkanoyloxyalkyl, hydroxyalkyl, alkylthioalkyl, CnH2nB, where n is 0-3 and B is an opt. satd. heterocyclic ring contg. one or two O, N ...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook uricosuric agents Medical Wikipedia Related to uricosuric agents:allopurinol,xanthine oxidase inhibitors Used to reduce the uric acid in the body, and thus to treat gout. ...
Uricosuric agents Uricosuric agents increase renal clearance of uric acid by inhibiting the renal transporters, particularly URAT1, in the proximal renal tubule (Fig. 2). Uricosuric agents should be used with caution in patients with a history of urolithiasis, and all patients taking uricosuric...
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美[ˌjʊrɪkə'sʊrɪk] 是什么意思 adj. 促尿酸尿的; 英英释义 uricosuric[ ,juərikəu'sjuərik ] adj.acting to increase the excretion of uric acid in the urine 学习怎么用 权威例句 uricosuric Uricosuric effect of radiocontrast agents. A study in man of four commonly...
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Elevation of the serum urate is well recognized as an invariable side effect of treatment with all diuretics except those agents, such as triamterene and amiloride, that retain potassium. Practitioners cannot fail to appreciate the frequency of hyperuricemia in many of their patients because, even in...
Effects of uricosuric and antiuricosuric agents on urate transport in human brush-border membrane vesicles The uricosuric diuretic, tienilic acid was 10 to 50 times more potent than hydrochlorothiazide, chlorothiazide and furosemide, for inhibiting [14C]-urate ... F Roch-Ramel,B Guisan,J Die...
Although it is fairly well established that these agents act by interfering with the reabsorption of uric acid by the renal tubular cells, the structural features required for this activity have not been defined. In the course of studies with one such drug, phenyl-butazone, a relationship ...
The uricosuric agent exerts a potent uricosuric\neffect on an animal experiment model while sustaining or gradually increasing\nthe urine volume. Further, it has a low toxicity. Thus it is useful in the\ntreatment of hyperuricemia or in the treatment and prevention of gout. It is\nexpected...