Several evolutionary changes have led to uric acid levels being much higher in humans than in other mammals. Uric acid is the end product of purine metabolism in hominoids, including humans, due to the genetic loss of uricase activity during the Miocene epoch, and this is the main cause of...
Uric Acid 纯度: 99.62% 产品编号 T0626 别名尿酸, Urate, Lithic acid, 2,6,8-Trioxypurine, 2,6,8-Trioxopurine, 2,6,8-TrihydroxypurineCas号 69-93-2 Uric Acid (Lithic acid) 是一种重要的抗氧化剂。Uric acid 能清除活性氧(ROS) ,如单线态氧和过氧亚硝酸盐,抑制脂质过氧化。Uric acid 有助于...
The objective of this study was to determine the effects of black tea on fasting uric acid levels and CRP in humans susceptible of cardiovascular diseases. Access through your organization Check access to the full text by signing in through your organization. Access through your organization ...
Despite the fact that observational studies have reported associations between serum uric acid (SUA) and depressive symptoms risk in East Asian populations, there is a lack of evidence demonstrating a causal relationship between them. This study aimed to perform a comprehensive assessment of the relati...
Fructose-Induced Hyperuricemia Is Associated With a Decreased Renal Uric Acid Excretion in Humans A letter to the editor is presented discussing the association between fructose-induced hyperuricemia with a decreased renal uric acid excretion in humans. V Lecoultre,L Egli,F Theytaz,... - 《Diabetes...
With considering serum concentration of the uric acid in humans we are observing hyperuricemia and possible gout development. Many epidemiological studies have shown the relationship between the uric acid and different disorders such are obesity, metabolic syndrome, hypertension and coronary artery disease....
Uric acid (UA) is the end product of purine metabolism in humans, it is formed from xanthine by xanthine oxidase enzyme through several steps and excreted into the urine. UA is endogenously synthesized mainly in the liver, intestines, muscle, and vascular endothelium [1, 2]. Exogenously, UA...
Abstract. Uric acid (UA) is the end product of purine metabolism in humans due to the loss of uricase activity by various mutations of its gene during the
in humans. However, highserum uric acidconcentration is also associated with several diseases, including several linked to increasedoxidative stress. Thus, the paradoxical role of uric acid as anti- and/or prooxidant has been the subject of an ongoing debate.Serum levelsof uric acid are regulated...
Uric acid: a potent molecular contributor to pluripotent stem cell cardiac differentiation via mesoderm specification Bingbing Ke, Yujie Zeng, Zhihong Zhao, Fusheng Han, Taoyan liu, Jingyi Wang, Anila Khalique, Wen-Jing Lu, James Chong, Feng Lan & Hua He Cell Death & Different...