The pool of uric acid in the body is about 1200 mg, out of which about half amount undergoes turnover daily, that is, about 600 mg/dl is formed daily and about the same amount is lost, of which about 75% is exerted through urine and about 25% destroyed by bacteria in the colon....
However,whenuric acidlevel becomes too high, either by excessive production or impaired removal by the kidneys,uric acidcrystals will form in various tissues in the body. shanghai.ufh.com.cn shanghai.ufh.com.cn 不过,当尿酸水平变得太高,尿酸产生过多或是肾脏的尿酸代谢功能减弱时,尿酸盐结晶就会沉...
The effect of the action of atophan upon the uric acid output in the urine and the decrease in the concentration of this substance in the blood begins to be manifest nearly as soon as absorption of the drug has taken place; and has exerted its maximum influence in about one day. With ...
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The color intensity of the reaction product at 570nm or fluorescence intensity at λex/em = 530/585nm is directly proportional to glucose concentration in the sample. Application Direct Assays: uric acid in serum, plasma, urine and other biological samples. Drug Discovery/Pharmacology: effects of...
Low uric acid On the other hand, uric acid is an antioxidant in the body and low levels can result in oxidative stress and endothelial dysfunction, which can predispose to illnesses such as hypertension and diabetes. Besides, a reduced uric acid concentration has been proven to contribute to mu...
41.3), which may reflect a decrease in net tubular reabsorption.8 As the pregnancy advances, fractional excretion of uric acid decreases, leading to an increasing plasma uric acid concentration, attaining levels close to the nonpregnant mean. Serum uric acid concentrations are significantly higher in...
Uric acid nephrolithiasis primarily results from low urinary pH, which increases the concentration of the insoluble undissociated uric acid, causing format... Nicola,Abate,Manisha,... - 《Kidney International》 被引量: 701发表: 2004年 Pathophysiologic basis for normouricosuric uric acid nephrolithiasi...
[100]. In late gestation, the UA concentration in maternal amniotic fluid is significantly higher than that in maternal venous serum or cord serum, which may be determined mainly by the urine produced by foetal excretion. The amniotic fluid UA concentration may also be an indicator of foetal ...
In late gestation, the UA concentration in maternal amniotic fluid is significantly higher than that in maternal venous serum or cord serum, which may be determined mainly by the urine produced by foetal excretion. The amniotic fluid UA concentration may also be an indicator of foetal maturity ...