2-NBDG assayC2C12 myotubesInsulin resistanceUnder type-2 diabetes, insulin resistance develops in skeletal muscles as a key defect and to study the disorder, its manifestation, and possible solution, measurement of glucose uptake is a fundamental necessity. Of various approaches (i.e. scintillation ...
as 2-NBDG transports into cells by the same glucose transporters (GLUTs) as glucose. Once 2-NBDG is uptaken in cells, it undergoes phosphorylation at C-6 position to give 2-NBDG-6-phosphate, which is well retained within the cells. Compared to other glucose tracers, such as 2-DG or FD...
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OGD significantly increased 2-NBDG uptake by about 1.2 to 2.5 times in astrocytes compared to control cells. These results show that 2-NBDG can be used to detect glucose transport in astrocytes exposed to OGD.Yan ChenDepartment of NeurologyJunjian Zhang...
寻标宝于2025-03-13发布中山医学院2-NBDGGlucoseUptakeCell-BasedKit2-NBDG葡萄糖摄取检测试剂盒,项目位于广东省,项目编号null。寻标宝为您提供广东省2025年最新的招标采购信息查询服务。
Compared with the normal pregnancy group, the weight of the fetus and placenta of GDM mice increased (P < 0.001), and the ability of trophoblasts to take up glucose decreased (P < 0.001). In addition, AMPK activity in trophoblasts and membrane localization of GLUT3 in GDM mice ...
Of two stereoisomers of glucose, only d- and not l-glucose is abundantly found in nature, being utilized as an essential fuel by most organisms. The uptake
求助可以测DPP4抑制活性和Glucose uptake by 2-NBDG glucose uptake assay的公司
The drawbacks of assessing the uptake for a single nutrient using enzyme-based assays are relatively high costs compared to the amount of data possible to extract from such experiment, whereas untargeted screening requires special equipment and highly trained personnel to analyze the output data. Howev...
The effect of mTORC1 on glucose uptake was confirmed using a liver-specific Tsc1- deletion mouse model in which FDG uptake was reduced in the livers of mutant mice compared with wild-type controls. Together, these data show that mTORC1 activity is insufficient for increased glycolysis in ...