Meaning These findings suggest that policies aimed against anticompetitive practices could allow biosimilars to enter the US market more quickly and could result in overall lower costs and that awareness of biosimilars should be promoted to increase uptake of biosimilars globally. Abstract Importance Biolo...
The feasibility study took place as pandemic storm clouds were gathering, which led to an early closure of the recruitment window, meaning that the full recruitment target was not reached. Recruitment rate was potentially impacted by COVID-19 related staff sickness and isolation, and diversion of ...
Attitude towards domestic violence is comprised of five scenarios to which the respondent answered ‘yes’, meaning it is justified, and ‘no’, meaning it is not justified. The scenarios include; beating justified if the wife goes out without telling the husband, neglects children, if food is...
In China in 2022, the biosimilar price was 69% to 90% of the reference drug cost, while uptake rates were 54% to 83%. Meaning This study found equivalent clinical outcomes and lower prices of cancer biosimilars vs reference drugs, suggesting that initiatives to increase uptake of biosimilars ...
The likelihood of action discusses factors in the probability of appropriate health behaviour; it is the likelihood of taking the recommended preventive health action [27]. In terms of its application to HTC, the model proposes that a person’s likelihood of engaging in particular health behaviour...
but the background information and choice tasks were tailored to the objectives of each survey. The survey used for the symptomatic adult DCE is provided as an example in the online SupplementaryMaterials. For each survey, there were 40 choice tasks split into four blocks, meaning that each par...
However, in cancer cells, this asymmetry is deregulated meaning that cells often expose PS in the outer membrane resulting in a negative surface charge, which correlates with a more acidic pH of extracellular media. Metabolic changes that cancer cells go through (increased anaerobic glycolysis) also...
In Nigeria, 53.3 million women are estimated to be at risk of developing cervical cancer (IARC/ICO, 2017) with a national standardized prevalence rate of 33.0 per 100,000. The Yoruba speaking people of Southwest Nigeria describes cervical cancer as “Jejere enu ile omo” literally meaning ...
Meaning These findings highlight the risk that blunt use may pose for subsequent cigar use among adolescents. Abstract Importance Almost two-thirds of adolescents who smoke blunts also report using cigars. Although adolescent co-use of blunts and cigars is prevalent, whether adolescent blunt use is...
Meaning These findings support the delivery of COVID-19 vaccine messaging platforms in EDs nationally to improve vaccine acceptance and uptake in underserved populations whose primary health care access occurs in EDs. Abstract Importance Large segments of the US population’s primary health care access...