The present invention relates to an isolated nucleic acid sequence which, as a promoter, is regulated in a developmental- and sex-specific manner. The sequence is useful in DNA constructs, in combination with a gene of interest, to achieve developmental and sex-specific expression of the gene ...
Upstream on the 5′ side of any given site in DNA or RNA and on the N-terminal side within a polypeptide (downstream). With respect to its transcriptional activity, upstream regions of a gene are on the 3′ side of any given region in the coding (sense) strand. Two-Hybrid SystemThis...
Haematopoiesis – the process by which pluripotent haematopoietic stem cells choose to become lymphocytes, myeloid cells, red blood cells or platelets – has long been a useful model to study cellular commitment and differentiation. Each cell type is defined by lineage-specific patterns of gene expres...
The dsx homologues are regulated by a series of upstream regulators that show amazing diversity in different insect species. These results support the Wilkin's hypothesis that evolution of the sex-determination cascade has taken place in reverse order, the bottom most gene being most conserved and ...
Enhancers can be upstream or downstream of the gene, even in the introns. 翻译结果2复制译文编辑译文朗读译文返回顶部 Enhancers can genes upstream or downstream even in intron. 翻译结果3复制译文编辑译文朗读译文返回顶部 Enhancers can upstream or downstream of the gene, even in intron. 翻译结果4复制...
providing reproductive fitness to the embryo. A gene is imprinted when one of the parental alleles is partially or completely silenced due to allele-specific epigenetic marks in chromatin and the other allele gets expressed. Among the imprinted genes that are paternally silent but maternally expressed...
an impermeable covering of the bottom of a reservoir adjacent to a dam or some other water-retaining hydraulic-engineering structure. An upstream apron is used to lengthen the path of the water that is seeping through beneath the structure and to reduce the uplift on the bottom of the structur...
During adipocyte differentiation, CCAAT/enhancer-binding protein α (C/EBPα) functions as a pleiotropic transcriptional activator of numerous adipocyte genes. The promoter of the C/EBPα gene has an E-box upstream of C/EBP binding site. Deletion or mutation of the E-box decreases promoter activ...
Although the formation of the cornified envelope is induced by tumor-promoting phorbol esters, the effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on the involucrin gene expression remains unknown. We have isolated a 5'-upstream region of human involucrin gene and examined its TPA-dependent ...
4) gene region 基因区域 1. Aiming at the problem of seeking the most possible gene regions to take the advantage of each gene predicting tool when various tools might predict various gene regions respectively,this paper brings forward a PSO algorithm of combining and optimizing multi predicted ...