and schematic representations of proteins were generated using Protter [17]. FoldX version 3.0 beta 6 [18] was used to predict the effect of the mutations on the thermodynamic stability and the interaction energy. Crystal structures were repaired using theRepairPDBcommand...
Beta-diversity analysis for longitudinal nasopharyngeal swab samples obtained from healthy and IAV-infected individuals. Principal coordinates analysis (PCoA) of Bray–Curtis distances was done for samples from humans, labeled as influenza positive in red (P, indicating data points with positive IAV qRT...
The pharyngeal structures and individual anatomic components within this region include the pharyngeal walls, the base of the tongue, the soft palate with uvula, and the epiglottis. The cross sectional area of the upper airway varies with the phases of the respiratory cycle. At the initiation of...
The barrier function of the nasal epithelium can be analyzed in vitro by performing absorption tests of labeled molecules, as has been done with the skin [113], in parallel to visualizing tight junction markers by immunofluorescence on tissue sections. Reproducing the immune function of the nasal ...