To ensure that existing projects work correctly, all existing Universal Renderer assets that were using any Renderer Features (excluding those included with URP) have the optionAlwaysselected in theIntermediate Textureproperty. Any newly created Universal Renderer assets have the optionAutoselected. ...
If you are using the Universal Render Pipeline (URP) you need to use the respective spine URP shaders (2D or 3D depending on your renderer), the normal standard multi-pass shaders don't work with URP.spine-unity Runtime Documentation: URP Shaders Extension UPM Package Please note the ...