neonatalinfantguidelineAmerican Academy of PediatricsFever in infants under age 60 days is a leading cause of ED, urgent care, and primary care visits. Most infants present as well-appearing, and guidelines for the workup and appropriate management of these children have varied over the decades....
In addition, the mother's platelet count does not predict fetal platelet count, and therapy of the mother is not known to affect neonatal outcome.223, 226, 227 Initial treatment Oral corticosteroids Low-dose corticosteroids are first-line therapy, although 1 retrospective study of 98 patients ...
Acute disseminated candidosis is the most severe form of systemicCandidainfection in neutropenic patients. It is characterized by hemodynamic instability, persistent positive blood cultures, and deep organ and/or skin involvement. Patients present with sepsis, spiking fever, shaking chills, and disseminated...
Host Response to Probiotics Determined by Nutritional Status of Rotavirus-Infected Neonatal Mice. J. Pediatr. Gastroenterol. Nutr. 2012, 55, 299–307. [Google Scholar] [CrossRef] [PubMed] [Green Version] Gutierrez-Castrellon, P.; Lopez-Velazquez, G.; Diaz-Garcia, L.; Jimenez-Gutierrez, C....
In CAPS (an entity consisting of familial cold autoinflammatory syndrome, Muckle–Wells syndrome and neonatal-onset multisystem inflammatory disease), anakinra has been shown to prevent and even reverse the manifestations, such as fever, rash, arthritis, fatigue, conjunctivitis, headache, papilledema, ...
Rozanolixizumab is a humanized IgG4 mAb targeting the neonatal Fc receptor (FcRn). FcRn is responsible for IgG recycling intracellularly, and inhibiting it leads to accelerated elimination of IgG. Rozanolixizumab, hence, reduces plasma IgG levels. Phase 3 trials have shown its efficacy and ...