Chronic obstructive pulmonary disease and low vitamin D status predict mortality, but their combined effect on mortality remains inconclusive. We aimed to investigate a joint effect of airway obstruction and vitamin D status on mortality in a nationally representative cohort. Methods: We analysed data ...
Redox signaling refers to the intricate interplay between reactive oxygen species (ROS) and antioxidant defense mechanisms, which impacts disease progression and pathogenesis. In CKD and HF, an imbalance between ROS production and antioxidant capacity leads to oxidative stress, exacerbating renal damage. ...
Hence, the novel infection, Coronavirus Disease 2019 (COVID-19), has become a global health threat, and in March 2020 the World Health Organization (WHO) declared it a global pandemic [4]. To date (as of 1 May 2022), the WHO has reported over 500 million confirmed COVID-19 cases ...
103 - N° 3 - p. 295-300 - Iconography : Current Use of Beta Blockers in Patients With Reactive Airway Disease Who Are Hospitalized With Acute Coronary Syndromes - EM|consulteBenjamin A OlenchockGregg G FonarowWenqin PanAdrian HernandezChristopher P CannonElsevier Masson...
Eosinophils play an important role in the pathogenesis of bronchial asthma and its exacerbation. Recent reports suggest the involvement of IFN-γ-inducible protein of 10 kDa (IP-10) in virus-induced asthma exacerbation. The objective of this study was to
p66Shc, a master regulator of mitochondrial reactive oxygen species (mtROS), is a crucial mediator of hepatocyte oxidative stress. However, its functional contribution to acetaminophen (APAP)-induced liver injury and the mechanism by which it is modulate
disease. the earlier bvas2 has been shown to have prognostic value and correlates with the validated 5-factor prognostic score[ 21 ]. bvas3 demonstrates concordance with bvas2, treatment decision, physician global assessment and c-reactive protein[ 21 ], however, further studies are required to...
expression in normoxic cells was increased to a similar level by DFX (250 μM), CoCl2(250 μM) and hypoxia (1%) for the same period of time (6 h). Because mitochondrial reactive oxygen species are reported to be regulators of HIF-1α and HIF-2α stabilization21, we then examined the...
24 - N° 1 - p. 133-140 - Iconography : Arylhydrocarbon receptor (AhR) activation in airway epithelial cells induces MUC5AC via reactive oxygen species (ROS) production - EM|consulteTakahito ChibaHiroshi UchiGaku TsujiHisaki GondoYoichi MoroiMasutaka FurueElsevier Masson...
Melanoma originates from the cells responsible for pigment production (melanocytes) and is the most aggressive of all forms, being likely to grow and spread if left untreated. Therefore, it is vital to diagnose this disease early and start treatment right away [113]. PDT is considered an ...