To date, very little data is available regarding the exposure to SNRIs during the pregnancy. A prospective cohort study was conducted on 6 pregnant women (W) in treatment with venlafaxine(V) or duloxetine(D), afferent to the Clinic of Affective Disorders in Pregnancy and Postpartum of the ...
Chappell AS, Desaiah D, Liu-Seifert H, et al. A double-blind, randomized, placebo-controlled study of the efficacy and safety of duloxetine for the treatment of chronic pain due to osteoarthritis of the knee. Pain Pract 2011;11(1):33-41. Lyttle JR, Urquhart DM, Cicuttini FM, et al...
Consider risk versus benefit Duloxetine (Cymbalta) of increased bleeding risk. Withholding may Levomilnacipran (Fetzima) result in a withdrawal syndrome. Consider Milnacipran (Savella) discontinuing either antiplatelet agent or Venlafaxine (Effexor) SSRI if patients are on concurrent ...
This might be a reasonable option if duloxetine has failed or contraindications are present. From the practical side, it is important to apply all of these suggested agents against neuropathic pain at least for 2 weeks at the appropriate dose in order to assess their efficacy before changing to...