Rapid GDMT titration programs have been shown to be effective in clinical trials. We evaluated the feasibility of a rapid GDMT clinical program in a safety-net population with HFrEF.#Methods:Patients admitted to a large urban safety net hospital with newly diagnosed HFrEF (LVEF <40%) were ...
The main findings of the study, compared with up-titration of the ARB valsartan, are as follows: (1) up-titration of the CCB nifedipine GITS produced no additional increased safety concerns; and (2) despite better BP reduction, up-titration of the CCB nifedipine GITS produced no change in...
To measure 5mC and 5hmC expressed on genomic DNA, total DNA was isolated using a Puregene Core Kit A (Qiagen). The amount of DNA to be used in the dot-blot assay was determined by titration of the sample with various concentrations of standard DNA. In all, 25 ng of DNA, which is...
Sertraline (SER), aka Zoloft, is one of modern antidepressant, it belongs to the selective serotonin reuptake inhibitor class, which functions to raise serotonin levels in the nervous system. SER has both mood-boosting and depressive effects but has bad influence on the gastrointestinal system. The...
Further drug titration was based on the results of these studies. The drug dose was adjusted and optimized by the treating physician in an attempt to achieve the preselected rate-control guidelines. If adequate rate control could not be achieved at a low dosage of medication, the dose was ...
Medication titration in patients with heart failure. As clinicians face growing responsibilities to keep up with continuing medical education offerings, they have less time to learn fundamental risk management knowledge to practice safely. To meet their clinicians' needs and time constrain... J Mayr...
20-22 Other content areas that are occasionally included in CBT-I, such as relaxation and medication titration, were not included (details are available in the eAppendix in Supplement 2). Online PE The online PE program provided nontailored and fixed material about insomnia symptoms and the ...
of goal-directed therapy for initial fluid management, which is defined as the titration of intravenous fluids to specific clinical and biochemical markers, such as the heart rate, mean arterial pressure, CVP, urine output, blood urea nitrogen, and haematocrit levels [22]. Although the use of ...
decrease in cravings for alcohol and sweets. The GLP-1 peptides have cardio-protective benefits and help slow down digestion, which emphasizes the importance of consuming nutrient-dense quality calories. The healthcare professional recommends micro-dosing and slow titration protocols to minimize side ...
Choice of medication and dose determined by treating physician (start morfine retard 2 daily doses of 10 mg or equivalent dose of another opioid; subsequent titration of dose should be guided by pain levels, development of tolerance and side-effects). The type and dose of medication will be ...