Methods: A single-center retrospective study was conducted on patients with a diagnosis of unresectable stage III NSCLC who underwent radical CRT followed or not by durvalumab. Tumor response after CRT, pattern of relapse, overall survival (OS) and progression-free survival (PF...
Patients with unresectable, histologically confirmed, stage IIIA/B NSCLC who were at least 18 years of age, treatment naive, have an ECOG performance status of 0 or 1, and acceptable laboratory and pulmonary function were enrolled to the single-cohort, phase 2 trial. They were re...
What multidisciplinary coordination is vital to optimizing care for patients with unresectable stage III NSCLC? Which specialists should be involved and what is their role on the treatment team? How do you ensure the multidisciplinary team is aligned on diagnosis, risk assessment, and treatment goals...
(RTTNews) - British drug major AstraZeneca PLC (AZN, AZN.L) announced Thursday that its Tagrisso (osimertinib) has been approved in the US for the treatment of adult patients with unresectable, Stage III epidermal growth factor receptor or EGFR-mutated lung cancer. The decision follows a...
EP: 3.PALOMA-3: Subcutaneous Amivantamab in Refractory EGFR-Mutated Advanced NSCLC EP: 4.Results from CROWN: Lorlatinib in Treatment-Naïve Patients with Advanced ALK+ NSCLC EP: 5.ADRIATIC: Durvalumab as Consolidation Treatment for Limited-Stage SCLCRecent...
Objectives: Unresectable stage III NSCLC (non small cell lung cancer) confers a poor prognosis and interest is growing in the use of immunotherapy to impro... Katakami, NobuyukiHida, ToyoakiNokihara, HiroshiImamura, FumioSakai, HiroshiAtagi, ShinjiNishio, MakotoKashii, TatsuhikoSatouchi, MiyakoHelw...
Define unresectable. unresectable synonyms, unresectable pronunciation, unresectable translation, English dictionary definition of unresectable. unresectable. Translations. English: unresectable adj irresecable. Spanish / Español: adj irresecable.
“Imfinzi has transformed the treatment of patients with unresectable, stage 3 NSCLC, and we’re excited by the promise of extending its benefit through novel combinations with 2 potential first-in-class monoclonal antibodies demonstrating strong clinical activity,” sa...
Notably, in September of 2024, the FDA approved treatment with osimertinib for adult patients with locally advanced, unresectable, stage III NSCLC. These were patients whose disease has not progressed during or following concurrent or sequential platinum-based chemoradiation therapy and whose tumors have...
The PACIFIC regimen is a new strategy for treating patients with stage III unresectable NSCLC and is the first major breakthrough in treatment for this indication for several years. ICB therapy is associated with irAEs, of which pneumonitis is potentially the most severe and life-threatening. Howe...