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All of the above technologies share a common weakness in that they are attacking tumor cells along a single axis of mechanism of action. They have shown that early incomplete clinical responses to single-mechanism drugs are often followed by relapse, due to the emergence of resistant tumor clones...
growth of local small businesses, transfer of new technologies, and creation of job opportunities for local skilled and unskilled labour. But out-migration for work has also added to the challenges in mountain areas. Increased out-migration