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Features characterizing oomycetes are usually based on biochemical studies focused on Phytophthora sp. and particularly, the presence of cellulose rather than chitin in their cell wall. However the presence of either chitin or chitosaccharides was observed in the Saprolegniale oomycetes Saprolegnia ...
Although long non-coding RNAs (lncRNAs) and mRNAs share many common features, several types of lncRNAs are distinguished from mRNAs by unique features of biogenesis, form and function. lncRNAs exhibit more highly specific expression patterns than mRNAs. Many lncRNAs undergo special processing events, ...
Clinical studies have long observed that neurodegenerative disorders display a range of symptoms and pathological features and, in some cases, overlap, suggesting that these diseases exist on a spectrum. Dementia with Lewy Bodies (DLB), a synucleinopathy, is a prominent example, where symptomatic sim...
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We have reviewed the unique structural, biochemical and functional features of the CD160 GPI-anchored NK cell receptor which differ in many ways from the other activating NK cell receptors. How this receptor and their specific ligands regulate the behaviour of NK cells in vivo in healthy and pat...
The tyrosine kinase-like (TKL) family of proteins are an unexplored set of kinases inToxoplasma. Of the eight annotated TKLs in theToxoplasmagenome, a recent genome-wide loss-of-function screen showed that six are important for tachyzoite fitness. By utilizing an endogenous tagging approach, we...
5. Loss of perlecan at tissue borders associated with pathology in vertebrates 6. Evolutionary origins reveal association with establishment of tissue function 7. Translating boundary functions into useful constructs for tissue engineering of multi-layered tissues 8. Summary and future directions Acknowledg...
the viral rhodopsin shows some unique features, such as a distinct structure of the cytoplasmic part, a bottle-shaped central channel and an unusual position of the proton donor. There is unexpected similarity between the organization of the vestibule in OLPVRII and unrelated pentameric ligand-gated...
Given this unexpected behavior we hypothesized that TcMVK may be a bifunctional enzyme, typified by having a second function not related to its original, classical function. In addition, many enzymes that are originally involved in metabolic pathways can also act as virulence factors of pathogenic ...