Standard pathologic factors are not good predictors of their outcome. For these patients new biologic markers need to be sought to distinguish between high and low risk and the treatment strategy for them should be guided by the aggressive characteristics of the disease....
The diagnosis of breast cancer is often delayed, resulting in their initial presentation with more advanced disease. Together, these characteristics lead to a poorer prognosis in younger women than in older women. Young women who receive breast-conserving therapy have a higher rate of local ...
There is controversy as to whether these differences are due to inter-racial genetic differences or to environmental or other factors.Using the Korean Breast Cancer Society's large breast cancer registry, we investigated the causes of Koreans' unique breast cancer characteristics by examining the ...
Innate lymphoid cells (ILCs) are a family of cells that includes circulating NK cells and several subsets of tissue-resident ILCs that are positioned at barrier surfaces and within tissues, allowing them to rapidly recognize and respond to dangers such as infection, tissue damage or cancer. This ...
However, their different potentials to maintain tumor growth and resist chemotherapy indicate a complicated cancer cell hierarchical organization in some tumors [6,19]. Analysis of abnormal cell lineages during carcinogenesis involves parallel verification of the characteristics and phenotypes of all types ...
we identify a subset of TPCs with higher glycolysis and enhanced pentose phosphate pathway and glutathione metabolism, characteristics that are strongly associated with a better antioxidant response. Together, our studies uncover enhanced glycolysis as a main driver in SCC, and, more importantly, identif...
. Studies of breast cancercell proliferation, adhesion, and survival on electrospun 2D and 3D PCLfibrous scaffoldshave been reported (Feng et al., 2013;Foroni et al., 2013;Rijal and Li, 2016). However, a synthetic 3D culture with strong infiltration of cancer cells into the depth of the ...
Conclusions TN breast cancers are associated with unique patient presentations, tumor characteristics, and clinical outcomes of which clinicians and investigators should be aware. 展开 关键词: Humans Carcinoma, Ductal, Breast Carcinoma, Lobular Breast Neoplasms Receptor, erbB-2 Receptors, Estrogen Receptors...
In the analysis of the co-localization of proteins involved in the process of MSCI, we considered several characteristics of the d(ri)starnibduitniodnivoidfuparloftleuinorse, sucseinngcescinattetenrsiptlioests,,wPheiacrhsownecreororbetlaatiinoendcuoseinffigcitehnetps l(urgp)-,Inovteenrlsait...
Fig. 1: Characteristics of the ginger genome. Distribution of genomic features of the ginger haplotype-resolved genome for haplotype 1 (green) and haplotype 0 (red). From inside to outside: (a) chromosome number, (b) gene density (0–220), (c) SSR density (0–0.002), (d) LTR densit...