John L. Francis, Ph.D., and the Heparin Consensus GroupUnfractionated heparin (UFH) is associated with a high rate of drug-relatedproblems due to either its inherent pharmacologic properties or an extensionof these
Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syn- dromes managed with an intended early invasive strategy: primary results of the SYNERGY randomized trial. JAMA 2004;292:45-54.Ferguson JJ,Califf RM,Antman EM,et al.Enoxaparin vs ...
Báo cáo y học: "Unfractionated heparin and enoxaparin reduce high-stretch ventilation augmented lung injury: a prospective, controlled animal experime... Unfractionated heparin and enoxaparin reduce high-stretch ventilation augmented lung injury: a prospective, controlled Chang Gung University,WHS Road...
Even in plasma fully depleted of antithrombin, the APTT can be prolonged to a therapeutic level, although the amount of heparin needed is twice as high. At antithrombin concentrations over 0.27 U/ml, heparin is the major determinant of the anticoagulant effect. 展开 ...
anti-Xa 0.3-0.7 - - Weak No: No significant association between anti-Xa level, aPTT, ACT, or heparin dose and thrombosis Drop et al. aPTT 60-85 or 50-70anti-Xa 0.5-1.0 or 0.3-0.7 0.37(0.19-0.69)c 0.49(0.31-0.63)c - No: No difference in anti-Xa in patients with or without th...
Objective To compare the clinical efficacy and influence on blood coagulation between low molecular weight heparin( LMWH) and unfractionated heparin( UFH) in the adjuvant treatment of elderly patients with severe pneumonia( SP). Methods 105 elderly SP cases were randomly divided into the LMWH group ...
\\{EVALUATION\\} \\{OF\\} \\{THE\\} \\{EFFICACY\\} \\{AND\\} \\{SAFETY\\} \\{OF\\} \\{OTAMIXABAN\\} \\{VERSUS\\} \\{UNFRACTIONATED\\} HEPARIN+EPTIFIBATIDE \\{IN\\} \\{PATIENTS\\} \\{WITH\\} NON-ST-ELEVATION \\{ACUTE\\} \\{CORONARY\\} \\{SYNDROMES\\} \\...
241 RISK OF SUPRATHERAPEUTIC APTT IN THE ABSENCE OF AN INITIAL UNFRACTIONATED HEPARIN BOLUS F Bonenfant, B Cossette, V Nault, M Turgeon, M Paulin, D Echenberg, P Charron, M Lépine, T Fayad, P Farand Sherbrooke, Québec BACKGROUND: Unfractionated heparin (UFH) is an anticoag- ulant ...
Anticoagulation Responses in Patients Receiving Low Molecular Weight Heparin Compared to Unfractionated Heparin for TEE Guided Cardioversion of Atrial Fibrillation: Results from the Assessment of Cardioversion Using Transesophageal Echocardiography (ACUTE II) Study...
unfractionated heparin compared to the saline-treated control group (all measurements below detection), as shown in Fig.1. There was also a significantly higher level of sFlt-1 in the media of BeWos treated with 1 U/mL (p< 0.0001) and 10 U/mL (p= 0.0230) unfractionated heparin ...