AGING IN THE BONE MICROENVIRONMENTThe bone is the third most common site of metastasis for a wide range of solid tumors including lung, breast, prostate, colorectal, thyroid, gynecologic, and melanoma, with 70% of metastatic prostate and breast cancer patients harboring bone metastasis.(1) ...
Metastasis is the process whereby cancer cells break free from a malignant tumor and travel to and invade other tissues in the body. Cancer cells metastasize to other sites via the lymphatic system and the bloodstream. Cancer cells from the original—or primary—tumor can travel to other sites ...
Metastasis is the process whereby cancer cells break free from a malignant tumor and travel to and invade other tissues in the body. Cancer cells metastasize to other sites via the lymphatic system and the bloodstream. Cancer cells from the original—or primary—tumor can travel to other sites ...
Metastasis is the process whereby cancer cells break free from a malignant tumor and travel to and invade other tissues in the body. Cancer cells metastasize to other sites via the lymphatic system and the bloodstream. Cancer cells from the original—or primary—tumor can travel to other sites ...
In addition, integrin-binding proteins promote invasion and metastasis in breast cancer. Targeting specific integrins and integrin-binding proteins may provide new therapeutic approaches for breast cancer therapies. This review will examine the current knowledge of integrins’ role in breast cancer. This ...
surgery, combination therapy, molecular targets associated with cancer growth and metastasis, and special emphasis on nanotechnology-based approaches for downregulating the deleterious disease. A detailed analysis with respect to types of nanoparticles and their scope in overcoming multidrug resistance as well...
Nature Reviews Cancer volume 7, pages 585–598 (2007)Cite this article 12k Accesses 760 Citations 20 Altmetric Metrics details Key Points Multiple myeloma is a currently incurable B-cell malignancy characterized by excess monotypic plasma cells in the bone marrow in association with an excess of ...
and release several immunomodulators to stimulate BC therapy resistance and escape from the anti-tumor immune response, which in turn promotes BC cell growth, invasion, and metastasis. c-DC1, type 1 conventional DCs; BC, breast cancer; BCSCs, breast cancer stem cells; MDSCs, myeloid-derived ...
In the cancer stem cell model, the modalities of cancer, such as initiation, progres- sion, metastasis and recurrence, depend primarily on rare stem cells. The heterogeneity and hierarchy between all of the cells within a tumor result from asymmetric division of CSCs. This model suggests that ...
Ramchandani D, Berisa M, Tavarez DA et al (2021) Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis. Nat Commun 12:7311 Article CAS PubMed PubMed Central Google Scholar Kalishwaralal K, Abhishek A, Keerthana CK et al (2023) Sele...