understand the primary differences between the two cell division processes, the importance of the maintenance of chromosome numbers in mitosis, the significance of the formation of germ cells with haploid number of chromosomes and the recombination events taking place during meiosis and their implications...
Exploring middle school students' conceptions of the relationship between genetic inheritance and cell division This study examines students' understanding of the normative connections between key concepts of cell division, including both mitosis and meiosis, and und... M Williams,AH Debarger,BL Montgome...
However, it is worth keeping in mind that the back-to-back orientation of sister kinetochores at mitosis and at meiosis II is rearranged to the side-by-side arrangement seen in meiosis I cells. Further, the accurate separation of homologues (reduction) depends on this rearrangement (figure 1;...
The microenvironment of the ovary is maintained by follicular fluid, and miRNAs carried by EVs in the follicular fluid are associated with follicular growth and oocyte maturation, proliferation of granulosa cells, cumulus expansion, meiosis and mitosis of the early embryo[65-67]. Female patients who...
Cells in the Bowman's capsule of the kidney that wrap around the capillaries of the glomerulus and filter urine. Meiotic DNA-damage response A checkpoint control that monitors meiotic recombination during meiosis, blocking the entry into metaphase I as long as recombination is not efficiently establi...
Both centrioles in the centrosome lose their orthogonal orientation towards each other at the end of mitosis and beginning of G1 phase. This event precedes new centriole formation. Half-bridge When a spindle pole body (SPB) is formed, it has a lateral structure, known as half-bridge. The...
In the past 15 years, impressive progress has been made to understand the molecular mechanism behind aneuploidy, largely due to the effort of using various -omics approaches to study model systems (e.g. yeast and mouse models) and patient samples, as well as the new realization that chromosome...
The Italian PhD student Sara Buonomo, also in Nasmyth`s team, was able to show in yeast that the same mechanisms that regulate chromosome segregation in mitosis are also at work in meiosis. The latest and most surprising news came from IMP group leader Jan-Michael Peters and his co-workers...
Meiosis is the step during which genetic recombinations occur in diploid spermatocytes and, at the end of which, haploid spermatids are generated. A single round of DNA replication is followed by two consecutive rounds of nuclear meiotic divisions. The first meiotic division (meiosis I) is ...
DNA methylation is predominantly maintained by DNMT1, which facilitates copying DNA methylation patterns during DNA replication in the S phase of mitosis and meiosis [37]. The epigenetic mark can then self-replicate because of DNMT maintenance, which recognizes mono-methylation and methylates the CpG...