During the last 5 years, the number of genes identified as causes of childhood epilepsies has increased significantly. Within this review, the current state of knowledge, rationale for genetic testingdoi:10.1007/s40124-017-0122-yHelbigIngo
A proportion of those receiving negative results following predictive genetic testing desire future bowel screening. This is despite a negative result meaning a general population risk of 1:7,500 and despite bowel screening being experienced as aversive and clinically unnecessary. This study aimed to ...
Studies have shown that patients with hypertrophic cardiomyopathy (HCM) may misinterpret the meaning of uninformative genetic testing results to mean that a genetic etiology and family members' risk is ruled out. We hypothesized that poor comprehension of the laboratory genetic test report may ...
genetic susceptibility test results Table 2 Free and prompted recall of Multiplex test results among a sample of 199 patients who received testing Health condition Correct recall of being at increased riska (free recall; %) Correct recall of test resultsb (prompted recall; %) Diabetes 70 94...
Let’s dive into cholesterol testing, the biomarkers this test measures, and how to understand your cholesterol tests results.
The results are summarized in Fig. 2, depicting the estimated proportion of genetic variance explained by discovered SNPs by both approaches as a function of sample size. The horizontal shift of the curve indicates that the effective sample size of MOSTest is generally about twice as high as ...
Qualitative interviews with 42 individuals who had undergone testing for a genetic susceptibility for deep vein thrombosis in primary and secondary care in the UK. Results Some participants, often from higher social classes, had a good understanding of the test and its implications. They had often ...
Type 2 diabetes mellitus results from the interaction of environmental factors with a combination of genetic variants, most of which were hitherto unknown. A systematic search for these variants was recently made possible by the developm... R Sladek,G Rocheleau,J Rung,... - 《Nature》 被引量...
The General Public's Understanding and Perception of Direct-to-Consumer Genetic Test Results Background/Aims: Direct-to-consumer (DTC) genetic testing allows consumers to discover their risk for common complex disorders. The extent to which consume... JW Leighton,K Valverde,Bernhardt, B.A. - ...
Genetic test results have important implications for close family members. Indeterminate negative results are the most common outcome of BRCA1/2 mutation testing. Little is known about family members' understanding of indeterminate negative BRCA1/2 test results. The purpose of this mixed-methods study...