Moreover, our analysis of theD. kotschyitranscriptome data to search the whole set of transcription factors (TFs) in PlnTFDB revealed that 6,626 assembled transcripts (6.20%) encode putative TFs. The predicted TFs can be classified into 50 TF families based on their DNA-binding domains (DBDs)...
Transposable elements and interspersed repeats made up 48% of the genome assembly (Supplementary Table5). The majority of the transposable elements belonged to long terminal repeat (LTR) retrotransposons (25.53%), followed by DNA transposable elements (12.67%). Among the LTRs, 40.75% and 23.88% r...
Well, this is my first post from behind the Grate Wall and I have to say it is very buggy. While Bl*gsp*t is outright prohibited wordpress on the other hand somehow squeaks by, but not without its lag and “connection reset” error boards. Really, who’s to say if this is at al...
These results are much like other observations in which increased levels of Velcade were used to treat a variety of cancers. Williams and McConkey [50] reported an increase in not only the stability of nuclear MDM2-P53, but also in the ability of the complex to bind a p53 DNA consensus ...
DNA (i.e. DNA that is not the focus of the study). While this is an important consideration in single genome studies (Goig et al.2020), it represents a particular challenge in mWGS, where host DNA likely to be highly prevalent in samples and hence constitute a significant fraction of ...
Cancer germline antigens: Cancer germline genes (for exampleMAGEA1,NY-ESO-1) are methylated and silenced in human adult tissue, except male germ cells and trophoblastic cells, which lack MHC-I molecules. Tumors often have aberrant patterns of DNA methylation, resulting in the demethylation, ectopi...
Since the 1990s, results coming in from molecular phylogenetics necessitate us to recognize that Horizontal Gene Transfer (HGT) occurs massively across all three domains of life. Nonetheless, many of the mechanisms whereby genes can become transferred la
In other words, such claims are to be understood as constructs initiated for various rhetorical reasons, such as claiming legitimacy on the grounds of a supposed ancient origin, rather than as empirically objective statements of genealogy (in contrast, see (Crivelli 2008)). Despite locating ideas ...