Mitochondria harbor multiple copies of their own genome (mtDNA), which in humans corresponds to a 16.5-kb circular molecule, responsible for the expression of 13 subunits of the oxidative phosphorylation complexes (OXPHOS).Rebolledo JaramilloBoris E...
Synthetic nucleic acid analogues have profoundly advanced our knowledge of DNA and RNA, as well as the complex biological processes that involve nucleic acids. As a pivotal enzyme, eukaryotic RNA polymerase II (Pol II) is responsible for transcribing DNA into messenger RNA, which then serves as ...
Understanding non-coding DNA regions in yeast: Figure 1 Non-coding transcripts play an important role in gene expression regulation in all species, including budding and fission yeast. Such regulatory transcripts include intergenic ncRNA (non-coding RNA), 5' and 3' UTRs, introns and antisense.....
G-quadruplex is a quadruplex consisting of four guanine and hydrogen bonds on DNA and RNA [122]. DNA helicase is required to break this structure prior to telomere elongation [123]. This structural change can upregulate or inhibit telomerase binding, and current research suggests that the stabilit...
Environmental DNA and RNA data can provide wider insights into fouling biodiversity How genetic information can help unravel the processes behind biofouling Accretion of calcareous deposition on marine surfaces Cathodic protection driven deposition Fig. 3: Visualization of calcareous deposition on marine surfa...
In this article, I review how our research on RNA began, how it led us to demonstrate the single-stranded nature of RNA, and the ways in which it differs from double-stranded DNA. It was based on the development of a method for the isolation of undegraded rRNA and the observation that...
An account of wheat chomosome structure in terms of DNA methylation, chromosomal proteins and meiotic chromosomes is presented. The classification of DNA sequences for complexity and DNA relationships within the Triticeae are considered. Other subjects covered are the use of DNA probes, introns, trans...
Preterm birth is a leading cause of infant mortality and can lead to poor life-long health and adverse neurodevelopmental outcomes. The pathophysiologic me... AP Sanders,HH Burris,AC Just,... - 《Epigenetics Official Journal of the Dna Methylation Society》 被引量: 21发表: 2015年 Urine cytolo...
M. et al. Microscopy-based chromosome conformation capture enables simultaneous visualization of genome organization and transcription in intact organisms. Mol. Cell 74, 212–222.e5 (2019). This article presents highly multiplexed sequential oligopaint FISH (RNA and DNA) based on the conjunction of ...
A conserved domain that is found in Argonaute-family proteins and that has structural similarities to RNase H. At least in some cases, it cleaves the RNA strand of an RNA–DNA helix. About this article Cite this article Rana, T. Illuminating the silence: understanding the structure and functi...