A thorough understanding of the cellular structure and function of tumor vessels becomes even more important, as this information is important to interpreting the effects of antiangiogenic agents, with the increasing hope of vascular targeting in cancer. This review intends to integrate our knowledge ...
Clarifying the structure and function of the triggers of the RNAi machinery and developing RNA-delivery technologies will increase the applicability of RNAi to biology and medicine. This, in turn, will enhance our understanding of the various cellular pathways that are controlled by small RNAs. ...
Nuclear pore complexes and nucleocytoplasmic transport: from structure to function to disease. Int. Rev. Cell Mol. Biol. 320, 171–233 (2015). Article CAS PubMed Google Scholar Hurt, E. & Beck, M. Towards understanding nuclear pore complex architecture and dynamics in the age of integrative...
A granuloma is a multifaceted cellular structure that serves to focus the host immune response, contain infection and pathology, and provide a niche for the bacillus to persist within the host. Granulomas form in response to Mycobacterium tuberculosis infection, and if a granuloma is capable of ...
The morphology of excitatory central synapses: from structure to function Synapses are the key elements for signal transduction and plasticity in the brain. For a better understanding of the functional signal cascades underlying ... A Rollenhagen,JHR Lübke - 《Cell & Tissue Research》 被引量: 11...
Abstract IA02: Slide-seq: A platform for understanding cellular circuits in tissue 来自 Semantic Scholar 喜欢 0 阅读量: 3 作者: F Chen 摘要: The precise spatial localization of molecular signals within tissues richly informs the mechanisms of tissue formation and function. Here we introduce Slide...
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and how positive and negative complement regulators perform their function. All of this has been made possible mostly because of the contributions of structural biology to the study of the complement components. The wealth of novel structural data has frequently provided support to previously held know...
et al. Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell 131, 174–187 (2007). CAS PubMed Google Scholar Cajigas, I. J. et al. The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution ...
Discovery and structure of a widespread bacterial ABC transporter specific for ergothioneine. Nat. Commun. 13, 7586 (2022). CAS PubMed PubMed Central Google Scholar D’Onofrio, N. et al. Diet-derived ergothioneine induces necroptosis in colorectal cancer cells by activating the SIRT3/MLKL ...