Further research is needed to elucidate how potential markers for liquid biopsy can be used to detect senescence and to search for innovative ways to overcome the limitations. Therapeutic opportunities for endothelial senescence Potential clinical implications of senescence have galvanized research into ...
I have watched 3 of my contemporaries die of prostate cancer (more likely the treatment) and 2 friends who have been severely crippled after contracting an infection from the biopsy, one here in UK and one in NZ. I have done extensive research on the internet but it wasn’t until I disc...
When radiation is directed to cancer cells, the radiation absorbed results in DNA damage and if severe enough, leads to cancer cell death. Unfortunately, surrounding normal tissue may be affected too. The aim of radiation therapy is to deliver effective doses of highly focussed radiation beams ...
Pattern diagram of the mechanisms of autoimmune diseases. After differentiation of hematopoietic stem cells, progenitor T cell (pro-T cell) will leave the bone marrow and enter the thymus, and differentiate from double-negative (DN) T cells into double-positive (DP) T cells. Under death by ne...
Biol Blood Marrow Transplant, 19 (11) (2013), pp. 1546-1556 View in ScopusGoogle Scholar 35 M Warren, S Jodele, C Dandoy, et al. A complete histologic approach to gastrointestinal biopsy from hematopoietic stem cell transplant patients with evidence of transplant-associated gastrointestinal thromb...
Targeted therapeutics are designed to focus on actionable mutations detected in a biopsy of the primary tumor, but these “actionable” mutations may no longer drive disease progression once tumor cells disseminate from the primary carcinoma and undergo unique genomic changes. The ability of single-cel...
40, 41 Nevertheless, primary human bile duct cells have been obtained from healthy human donor liver biopsy specimens and expanded in vitro into three-dimensional organoids. These cells preserve their genetic stability on long-term culture and differentiate into functional hepatocytes both in vitro ...
Results Seven patients met study criteria. All were male, 2 to 16 years of age. All had eyelid or forehead swelling and osteolytic defects, with symptoms of 2 to 6 weeks' duration. All underwent incisional biopsy, with frozen-section examination suggestive of LCH in 6 of 7 cases. The 2...
intrahepatic fat as well as with the pattern of CD36 expression in the liver. In this connection, a previous study from our laboratory described that serum level of sCD36 increased in NAFLD patients diagnosed by liver biopsy compared to subjects with histologically normal liver, and correlated ...
The spatial position within the tumour from which the biopsy was taken — central versus margin. If ‘normal’ fibroblasts are isolated at the same time from non-cancerous tissue, then the distance of this tissue from the margin should be recorded. ...