their drug regimen, and their accelerated growth and malignancy. It explores the fundamental differences between highly aggressive cancers and the less aggressive, more treatable ones. Especially, it focuses on their underlying principles on the fundamental...
Many bacteria can form wall-deficient variants, or L-forms, that divide by a simple mechanism that does not require the FtsZ-based cell division machinery. Here, we use microfluidic systems to probe the growth, chromosome cycle and division mechanism of
Towards closing this gap, we first present the importance and possible ways of energy saving in SDN, and then examine the principles, benefits and drawbacks of up-to-date SDN approaches that take energy efficiency into account. We also present a brief comparison of possible energy gain ratios ...
their drug regimen, and their accelerated growth and malignancy. It explores the fundamental differences between highly aggressive cancers and the less aggressive, more treatable ones. Especially, it focuses on their underlying principles on the fundamental...
The problem here is that there are no compelling principles guiding the individuation of samples (of a process whose trials are independent); but if arbitrary divisions of (independent) trials into multiple samples is permitted, then we are in trouble, because we could easily divide the 1000 ...
Together, our results provide critical insights into the mechanistic principles by which ligand-binding allosterically gates InsP3R channel. Cell Research (2018) 28:1158–1170; https://doi.org/10.1038/s41422-018-0108-5 INTRODUCTION Inositol 1,4,5-trisphosphate receptors (InsP3Rs) constitute a ...
Embryonic development involves massive proliferation and differentiation of cell lineages. This must be supported by chromosome replication and epigenetic reprogramming, but how proliferation and cell fate acquisition are balanced in this process is not
n of groups from left to right: 35,450, 209, 54. Points and error bars in a,e represent median and 95% confidence intervals as computed by 200 bootstraps (see Methods). Full size image We next assessed whether similar principles of selective sensitivity to SOX9 dosage apply to normal-...
mRNAs, proteins and the emerging principles of gene expression control Nat. Rev. Genet., 21 (2020), pp. 630-644, 10.1038/s41576-020-0258-4 View in ScopusGoogle Scholar 29 M.J. Gandal, P. Zhang, E. Hadjimichael, R.L. Walker, C. Chen, S. Liu, H. Won, H. van Bakel, M. Va...
2, it should be understood that the principles of the examples may be similarly extended to other computing environments and to other virtual PVs composed of more or fewer underlying storage volumes. In an example, a snapshot type storage operation request 290 (also referred to herein as a ...