UNDERLYING CORONARY ARTERY DISEASE POTENTIATES THE ANTIARRHYTHMIC EFFICACY OF DOFETILIDE ON ATRIAL FIBRILLATIONdietexerciseheart defects, congenitalobesityrisk factorsBackground-The tumor necrosis factor receptor superfamily, which includes CD40, LIGHT, and OX40, plays important roles in atherosclerosis. CD137...
Genetics is estimated to account for 50% of Coronary Artery Disease (CAD) risk. Genome-Wide Association Studies (GWAS) have revealed 100s of genomic loci which are associated with CAD (1). However, moving from GWAS signals to causal genes has proved challenging, slowing progress in developing...
The most common conditions were diabetes, chronic lung disease and cardiovascular disease, but the agency also found a higher risk among smokers and people with hypertension, renal disease and coronary artery disease. CDC said many of those conditions are common in the U.S., which unde...
We performed an expression quantitative trait locus (eQTL) analysis on 966 deconvoluted bulk RNA-seq samples, including adult (atrium, ventricle, aorta, and coronary artery) and fetal-like (iPSC-CVPCs) tissues, and identified cardiac eQTL signals associated with 11,692 eGenes and 7165 eIsoforms....
and developing and tracking health goals to keep preventable illnesses, like chronic lung disease or coronary artery disease, at bay.A regular primary care physician allows continuity of care between the doctor and the patient so that the doctor is better able to understand the patient’s body an...
It affects mostly young women without coronary risk factors and is usually associated with fibromuscular dysplasia. SCAD has an underlying disease in 80% of patients. SMAD3 mutation has been linked to aneurysm-osteoarthritis syndrome and has been identified as a cause of familial thoracic aortic ...
JAMA. 2003;290(12):1624-163214506122ArticlePubMedGoogle ScholarCrossref Reassessment of Clinical Practice Guidelines JAMA Editorial February 25, 2009 See More About Acute Coronary Syndromes Cardiology Guidelines Health Care Quality Ischemic Heart Disease Trending The Quality of Evidence Supporting Clinical Pr...
less sedentary behavior and higher physical activity levels are also genetically correlated with a more favorable cardiometabolic status, including lower triglyceride, total cholesterol, fasting glucose and fasting insulin levels, and lower odds of type 2 diabetes and coronary artery disease; as well as...
Association of aortic valve sclerosis and coronary artery disease in patients with severe nonischemic mitral regurgitation Background : The presence of aortic valve sclerosis accounts for a higher rate of ischemic events and increased cardiovascular mortality. It may reflect co... A Rossi,G Bertagnol...
Summary results for the main analyses have been made available through the Cardiovascular Disease Knowledge Portal (https://cvd.hugeamp.org/downloads.html; direct download usinghttps://personal.broadinstitute.org/ryank/Ellinor_ukbb_200k_exome.zip). Access to individual-level UK Biobank data, both...