Introduction: More than a decade of randomized controlled trials in prostate cancer have established a positive radiation dose response at moderate doses and a consistently low α/β ratio in the linear quadratic model for moderate hypofractionation. The recently published large randomized trial of ...
Objectives: To report toxicity (primary endpoint) and biochemical disease-free survival (BDFS) outcomes of a phase II trial evaluating ultra-hypofractionated radiation therapy (UHRT) focusing on unfavorable intermediate-risk (UIR) and high-risk (HR) prostate cancer (PCa) patients. Patients and ...
The drive towards hypofractionated prostate radiotherapy is motivated by a low alpha/beta ratio for prostate cancer (1 to 3Gy) compared to surrounding organs at risk, implying an improved therapeutic ratio with increasing dose per fraction. Early evidence from studies of ultrahypofractionated (UHF) ...
Results We identified 16 publications that reported the use of ultrahypofractionated radiation therapy to treat the pelvis in prostate cancer. Seven publications met our criteria and were included in the meta-analysis, including 417 patients. The median total dose to the pelvic lymph nodes was 25 ...
Moderate hypofractionated post-prostatectomy radiation therapy is feasible and well tolerated: experience from a single tertiary cancer centre Article 12 January 2021 Post-operative hypofractionated radiotherapy for prostate cancer: a mono-institutional analysis of toxicity and clinical outcomes Article 30...
To study the relationships between absorbed dose to penile base structures and erectile dysfunction (ED) in patients treated with ultrahypofractionated (UHF) radiation therapy (RT) or conventionally fractionated (CF) RT for prostate cancer.This dose-response study comprises 673 patients (57%) of the...
Njoynuclear data processing system simplified workflow. RECONR resconstructs PENDF cross sections from ENDF; BROADR computes Doppler-broadened cross sections; UNRESR computes self-shielded cross sections in the unresolved range; HEATR produces heat KERMA and radiation damage cross sections; THERMR compute...
Njoynuclear data processing system simplified workflow. RECONR resconstructs PENDF cross sections from ENDF; BROADR computes Doppler-broadened cross sections; UNRESR computes self-shielded cross sections in the unresolved range; HEATR produces heat KERMA and radiation damage cross sections; THERMR compute...
1740: Outcomes and late toxicities with ultra-hypofractionated radiation in non-metastatic prostate cancer doi:10.1016/S0167-8140(24)02082-6Radiotherapy and OncologyAnkita MallickShashank ShenoyMoses ArunsinghIndranil Mallick
2921: Prostate cancer ultra-hypofractionated RT: Does MRI-guided adaptation improve therapeutic ratio? doi:10.1016/S0167-8140(24)03031-7Radiotherapy and OncologySophie E. AlexanderRobert A. MitchellKian MorrisonJayde NarteyRosalyne WestleyUwe OelfkeHelen A. McNairAlison C. Tree...