There was a female:male ratio of 3.9:1. In women, the incidence of distal radius fracture rose from a premenopausal baseline of 10 per 10,000 population per year to a peak of 120 per 10,000 population per year
Inclusion criteria were women and men aged between 50 and 75 years old who were not known to be deaf, existing hearing aid or cochlear implant users based on READ coded information in their GP medical records. READ is the UK diagnosis coding system developed by Dr. James Read in the early...
Twin studies reveal evidence for moderate overall heritability for depression [27,28,29] with some evidence for greater heritability in women and for sex-specific genetic pathways to MDD (e.g., [28,30]). Despite the evidence for sex-specific molecular mechanisms for depression, genome-wide asso...
Differential media- tion and moderation among men and women were also tested in parts of the analyses. Materials and methods Database The UK Biobank is a population-centric research initiative designed to enhance illness prevention, diagnosis, and treatment [22]. The study collects data from ...
To study longitudinal trait change we first model the average population trait-change, and then determined the genetic influence on deviations from the population average. Modelling the population average is important as our data are both cross-sectional and longitudinal. For example, 2 identical ...
Subgroup byOdds ratio95% CIOdds ratio95% CI Gender Men N (unemployed) = 305 Women N (unemployed) = 253 Underweight 5.99 2.27–15.80 2.81 1.17–6.75 Overweight 0.58 0.41–0.82 0.94 0.65–1.35 Obesity 0.87 0.60–1.24 1.18 0.82–1.70 Household income Above median N (unemployed) = 90 Below me...
Fig. 3: Population structure, virulence, and antimicrobial resistance gene profiles of IEStreptococcus mitisin context of global isolates. aFrequency plot of the STs identified across the combined IE and globalS. mitisdataset. The plot shows that the UK IES. mitisbelonged to unique STs, however,...
This study finds elevated ON risk among young women, as has been reported previously (female-male ratio between 1.5:1 and 2.5:1).18-20,23 This finding is possibly driven by strong association with MS in the UK population.5,21,24,25 A further explanation is that many genes associated with...
In the full sample, there were more women than men (59% compared to 41%), with participants fairly evenly spread across the age range from 40 to 70 years at baseline (Fig. 3). Eighteen per cent of participants were obese (with body mass index > 30 kg/m2...
Overall, rates of microbial isolation from UK Biobank participants are of similar order and pattern to those seen in the general population (Tables 3, 4). As expected, there is a higher rate of isolation of E. coli in women than in men (e.g., for samples sent from general practice set...