Uridine diphosphate-α- d -glucose 6-dehydrogenase (UGDH, EC 1.1.1.22) is the four-electron transfer enzyme responsible for the oxidation of 6-hydroxyl group of UDP-α- d -glucose (UDP-Glc) to produce UDP-α- d -glucuronic acid (UDP-GlcA). The latter is the substrate for numerous ...
and tremor, which were often present prior to onset of seizures. Twenty-four out of the 30 (80%) were noted to have swallowing difficulties and gastrostomy tubes were required for feeding in 12 infants. None but two patients (F5-II:1 and II:2) achieved sitting ability. A moderate to se...
翻译结果1复制译文编辑译文朗读译文返回顶部 UDP-葡萄糖脱氢酶,推测[蓖麻] 翻译结果2复制译文编辑译文朗读译文返回顶部 UDP 葡萄糖 6-dehydrogenase,推定 ( Ricinus communis) 翻译结果3复制译文编辑译文朗读译文返回顶部 UDP-葡萄糖 6-脱氢酶,指认 [蓖麻] 翻译结果4复制译文编辑译文朗读译文返回顶部 udp-葡萄糖6-率...
Locus of the catalytic sites of udp-glucose dehydrogenase in the native enzyme hexamer as delineated by fluorescence energy transferdoi:10.1016/s0006-3495(80)84940-xFranzen, James S.Marchetti, PaulFeingold, David S.Elsevier BVBiophysical Journal...
In N. Taniguchi, K. Honke, M. Fukuda, H. Narimatsu, Y. Yamaguchi, & T. Angata (Eds.), Handbook of glycosyltransferases and related genes (pp. 1425-1437). Tokyo: Springer.glucose dehydrogenase (ugdh), and two other ORFs (Ali et al., 2005). In PBCV-1, the...
UDP-glucose-6-dehydrogenase (UGDH) plays an important role in the production of hyaluronic acid, an extracellular matrix component that is responsible for the promotion of normal cellular growth and migration. Increased levels of UGDH have been linked to the progression of epithelial cancers, such ...
UDP-6- glucose dehydrogenase (UGDH) is an enzyme that has become a recent oncologic target of interest across various cancer subtypes for its role in increasing the aggressiveness and migratory capacity of tumor cells both in vitro and in vivo. UGDH is ubiquitously expressed and plays a critical...
He, F.S. Wang, Use of induction promoters to regulate hyaluronan synthase and UDP-glucose-6- dehydrogenase of Streptococcus zooepidemicus expression in Lactococcus lactis: a case study of the regulation mechanism of hyaluronic acid polymer, J. Appl. Microbiol. 107 (2009) 136-144....
UDP-glucose dehydrogenase catalyzes the NAD + -dependent twofold oxidation of UDP-glucose to give UDP-glucuronic acid. A sequestered aldehyde intermediate is produced in the first oxidation step and a covalently bound thioester is produced in the second oxidation step. This work demonstrates that the...
Inhibition of UDP-glucose dehydrogenase by 6-thiopurine and its oxidative metabolites: Possible mechanism for its interaction within the bilirubin excretion pathway and 6TP associated liver toxicity6-ThiopurineUDP-glucuronic acidGlucuronidationDrug metabolism...