别名:UDPAG, UDP-GlcNAc, Uridine-5'-diphosphate-N-acetyl-D-Glucosamine 分子式:C17H25N3O17P2·2Na [XH2O] 分子量:651.3 纯度:>98% 溶解度:PBS (pH 7.2): 10 mg/ml 储存:-20°C 库存:现货 Background UDP-N-acetyl-D-Glucosamine is a natural nucleotide sugar that is used by glycosyltransferas...
KNEIDINGER B,O‘RIORDAN K,LI J,et al.Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-d-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11and capsule in Staphylococcus aureus type5 implications for the UDP-N-acetyl-1-fucos-amine b....
LpxH catalyzes the fourth step of the lipid A biosynthesis pathway and cleaves the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP. Here we present the structures of LpxH from Pseudomonas aeruginosa (PaLpxH). PaLpxH consists of ...
UDP- N -acetyl-D-glucosamine:伪-6-D-mannoside 尾-1,2- N -acetylglucosaminyltransferase II (EC 2.4.1.143) (GnT II) is a Golgi resident enzyme that catalyzes an essential step in the biosynthetic pathway leading from high mannose to comple... M Sarkar,E Hull,Y Nishikawa,... - 《Proce...
UDP- N -acetylglucosamine 2-epimerase/ N -acetylmannosamine kinase ( EC5.1.3.14 /2.7.1.60), the key enzyme of N -acetylneuraminic acid biosynthesis ... S Hideo,H Akira,N Toshihiro,... - 《Yakugaku Zasshi-journal of the Pharmaceutical Society of Japan》 被引量: 28发表: 1984年 Metabol...
It is anchored to the cell surface by an inositol–ceramide structure, and it is composed of L-rhamnose (L-Rha), N-acetyl-D-galactosamine, D-galactose, N-acetyl-D-glucosamine, D-glucose (D-Glc), and D-xylose. L-Rha forms an α1,3-linked polymeric backbone, from which lateral poly...
It is also used in the GlcNAc moiety of N-linked glycosylation and the GPI-anchor of cellular proteins (5). Biosynthesis of UDP-GlcNAc has been extensively studied in bacteria, and it requires the following enzymatic reactions: i) conversion of fructose-6-phosphate (Fru-6-P) into glucosamine...
An enzyme instrumental in bacterial cell wall biosynthesis is UDP-N-acetylenolpyruvylglucosamine reductase (MurB). MurB catalyzes the NADPH-dependent reduction of enolpyruvyl-UDP-N-acetylglucosamine (enolpyruvyl-UDP-GlcNAc) to the corresponding d-lactyl compound UDP-N-acetylmuramic acid (UDP-MurNAc)...
Neu5Ac is formed in vivo by a multistep pathway (Roseman 1970) beginning with the conversion of fructose-6-P to glucosamine-6-P, which is further metabolized to UDP-N-acetylglucosamine (UDP-GlcNAc), the crucial precursor of Neu5Ac, by the hexosamine pathway. This substrate is converted ...
UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT (CAS 91183-98-1, C17H28N3NaO17P2), is a white solid, widely used in biochemical research and pharmaceutical industry, with the special property of being a key intermediate in the biosynthesis of glycoproteins and glycolipids. It plays a crucial ...