The potential applicant must have a higher university degree (M.Sc. or equivalent) in a relevant field (e.g. mathematics, physics or computer science) and the ability to complete the doctoral degree within the normative duration of the studies for the degree (four years). The applicant is e...
when transduced into HUH7 liver carcinoma cells at a Multiplicity of Infection (MOI) of 1×107vg/cell, does not affect endogenous levels of α-galactosidase A transcript (top left panel) but expresses high levels of codon-optimised α-galactosidase A mRNA (top right panel)...
may be determined by sequence comparison and alignment algorithms known in the field. To determine the percent identity of two nucleic acid sequences (or of two amino acid sequences), the sequences are aligned for optimal comparison purposes (e.g., gaps can be introduced in the first ...