Ubiquitin-rhodamine 110 is a quenched, fluorescent substrate for deubiquitylases, especially ubiquitin C-terminal hydrolases. Cleavage of the amide bond between the C-terminal glycine of ubiquitin and rhodamine results in an increase in rhodamine fluores
泛素-罗丹明110是用于去泛素化酶的猝灭的荧光底物,尤其是泛素C-末端水解酶。泛素的C末端甘氨酸和罗丹明之间的酰胺键的裂解导致535nm处的罗丹明荧光(485nm激发)的增加。 序列 无 来源宿主 无 溶解建议 建议收到产品后溶解在DMSO的水溶液中。 保存建议 ...
Cleavage of the amide bond between the C-terminal glycine of ubiquitin and rhodamine results in an increase in rhodamine fluorescence at 535 nm (Exc. 485 nm). Application: Measurement of deubiquitylase activity. Product Information Purity: > 95% by RP-HPLC Molecular Weight: 8934.2 Da Physical ...
Herein, via high throughput screening based on Ubiquitin-rhodamine-110 (Ubiquitin-Rho-110) fluorometric activity assay, we discovered a novel inhibitor DC-U43. By structure optimization, DC-U43-10 reached a half-maximal inhibitory concentration (IC50) value of 2.6±1.1 μM and exhibited 10-fold...
tetraubiquitin-rhodamine110(Cat.#SI233;K63-linked Ub4;green)at100nMastheincreaseinfluorescenceat 535nmovertime. Allproductsareforresearchuseonly•notintendedforhumanoranimaldiagnosticortherapeuticuses Copyright©2013LifeSensors,Inc.AllRightsReserved ...
Ubiquitin-Rhodamine is prepared by the C-terminal derivatization of ubiquitin with modified rhodamine-110 and has been shown to be a useful and sensitive fluorogenic substrate for wide range of deubiquitinylating enzymes (DUBs), including ubiquitin C-terminal hydrolases (UCHs) and ubiquitin specific ...
SI230: Ubiquitin-Rhodamine SI-0230 Ubiquitin Chains and Derivatives, Ubiquitin Derivatives $387.00 –$2,743.00 SI230: Ubiquitin-Rhodamine quantity Add to cart SI233: K63-linked Tetraubiquitin-Rhodamine 110 SI-0233-0050 Proteasomal Research Tools, Ubiquitin Chains $941.00 SI233: K63-linked Tetraubiq...
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The split domain retains catalytic function on the minimal substrate ubiquitin–rhodamine 110-glycine (Ub–Rhod)27 (Supplementary Fig. 1D). Crystal structure of USP4 D1D2. We crystallized and deter- mined the structure of USP4 D1D2 by molecular replacement using the USP8 catalytic domain (PDB...
(Rhodamine 110)| 基本信息 更多信息 中文名称: 中文同义词: 英文名称: Ubiquitin (human) (rec.) (Rhodamine 110) 英文同义词: Ubiquitin (human) (rec.) (Rhodamine 110) CAS号: 分子式: 分子量: 0 EINECS号: 信息错误报告 您的Email: 按国家浏览Ubiquitin (human) (rec.) (Rhodamine 110)...