phospholipase C with the signal pathway PI3K/ PTEN, a ubiquitous mechanism for the control of chemotaxis and cell shape in free-living amoebae and mammalian tissue cells, has been investigated in Physarum polycephalum plasmodium, a multinuclear amoeboid cell with the autooscillatory mode of motility...
In summary, the data presented are in agreement with the idea that both U73122 and U73343 act downstream of phospholipase C to inhibit receptor-mediated phospholipase D activation in CHO–CCKA cells. Regarding the mechanism underlying the inhibitory action of the two aminosteroids evidence is pro...
However, the mechanism of PLC activation in a cell physiology under stress conditions remains unclear. Since the expression and activity of Hsp70 can be controlled by the increase of intracellular Ca2+ and by protein kinase C, whereas PLC itself is able to regulate these factors, it seemed that...