MS技术分析经典名方芍药甘草汤的化学成分2.基于UHPLC-Q-Exactive Orbitrap-MS技术分析桂附地黄丸的化学成分及入血成分3.经典名方温胆汤入血成分的UPLC-QE-Orbitrap-MS技术分析鉴定4.基于UHPLC-Q-Exactive Orbitrap MS技术分析不同干燥方法对人参皂苷类成分的影响5.基于UHPLC-Q-Exactive Orbitrap HRMS技术分析痔血...
采用超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UHPLC-Q Exactive Orbitrap HRMS)鉴定红花逍遥片的化学成分谱;依据组方原理将其划分为疏肝解郁组,活血调经组... 陈可点,陈文佳,刘雪婷,... - 《药学学报》 被引量: 0发表: 2024年 藿香正气口服液物质基础与质量控制研究 UHPLC/Q-Orbitrap-MS技术的的平行...
目的基于UHPLC-Q-ExactiveOrbitrapHRMS技术鉴定仙鹤草中的化学成分.方法色谱分离采用ACQUITYUPLCBEHC_(18)色谱柱(100mm×2.1mm,1.7μm),以0.1%甲酸水溶液(A)-甲醇(B)为流动相体系,梯度洗脱,流速0.3mL·min~(-1),柱温40℃.质谱采用加热电喷雾离子源(H-ESI),在正负离子一级全扫描结合数据依赖二级扫描模式(Full...
根据各原型成分在原方,血清及各组织中的均一化峰面积,可知栀子新苷,黄连碱,小檗碱,巴马汀,药根碱,黄柏碱 等成分在肝,肾等组织中有较大的暴露量.结论 借助 UHPLC-Q-Exactive Orbitrap HRMS 技术系统,准确,快速地实现了 黄连解毒汤化学成分鉴定,并揭示了黄连解毒汤大鼠 ig 给药后主要成分的组织分布特征,为...
基于UHPLC-Q-Exactive Orbitrap HRMS 和 HPLC-UV 的 石吊兰化学成分定性与定量研究doi:10.19540/j.cnki.cjcmm.20230414.201刘春花谢家丽付昌丽陆苑潘洁刘亭李勇军王永林黄勇孙佳China Journal of Chinese Materia Medica
In this study, 50% methanol extracts of BFT and FFT were analyzed via UHPLC-Q-Exactive Orbitrap MS/MS, and the feasibility of using non-targeted UHPLC-HRMS metabolomics and molecular networking to address the authentication of bulb and flower samples was evaluated. Principal component analysis (...
全扫描和 MS/MS 模式下的正 / 负离子切换模式能全面鉴定降解产物。数据分析软件 Mass Frontier 极大的提高了降解产物结构解析的速度和可靠性。Q Exactive Focus 台式 Orbitrap MS 具有强大的功能,能快速高效地完成降解产物分析,从而显著提高了药物研发过程中降解产物的鉴定通量。
A specific UHPLC-Q-Orbitrap HRMS method was developed as a reliable, sensitive and high-throughput method for rapid identification of the components of XBJ regardless of the macro- and micro-constituents. The total ion chromatograms (TIC) of the XBJsample both in positive and negative ion mode...
To clarify and quantify the chemical profiling of XueBiJing injection (XBJ) rapidly, a feasible and accurate strategy was developed by applying ultra high performance liquid chromatography-Q Exactive hybrid quadrupole-orbitrap high resolution accurate mass spectrometry (UHPLC-Q-Orbitrap HRMS). A total ...
doi:10.19540/j.cnki.cjcmm.20240311.202刘春花付昌丽孙佳陆苑潘洁李勇军王永林黄勇潘卫东China Journal of Chinese Materia Medica