After STV-pulldown, the Intu N-terminus containing PDZ domain (CBP-SBP-Intu ∆268-942) precipitated endogenous STAT1 while the mutants lacking this domain did not. f Intu and STAT1 interaction during IFN-γ, azide, and cisplatin treatment. 293FT cells were transfected with Intu constructs...
Inventors:Peter D. Jackson(Alpharetta, GA),Jeffrey S. Tadin(Canton, GA),Stephen R. Burns(Cumming, GA),Jacob M. Sclare(Dacula, GA),James E. Cartabiano(Gainesville, GA) Primary Examiner:Kien Nguyen Attorney:Alston & Bird LLP Application Number: 11/036,199 ...