Post-Entry Market Analysis of New Drug for Diabetes: Penetration and Concentration of Thiazolidinediones (TZD)new drugmarket penetrationmarket concentrationRationale: Adoption and penetration of new drug in medical care, a highly-regulated industry, is an essential issue in terms of access to new ...
Finding the functional link between PPARG and sclerostin is of great importance, because both proteins are pharmacological targets for existing therapies to treat diabetes and osteoporosis, respectively. This finding provides means to explore therapeutic overlap between anti-diabetic and anti-osteoporotic the...
Metabolomics characterization of perturbation effects of human adipocytes would provide rich metabolic pathway information for studying diabetes and facilitating drug discovery and therapeutics. Differentiated adipocyte cells, derived from adult mesenchymal stem cells, were cultured in adipogenic maintenance medium...