( 1966 ) The tyrosine hydroxylase activity of mammalian tyrosinase . J. Biol. Chem. , 241 , 161 – 168 .Pomerantz SH (1966). The tyrosine hydroxylase activity of mamma- lian tyrosinase. Journal of Biological Chemistry, 241: 161-168.
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The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous...
Inhibition of L-tyrosine-induced micronuclei production by phenylthiourea in human melanoma cells. Mutat. Res. 1999, 446, 143–148. [CrossRef] 21. Du, B.K.; Erway, W.F. Studies on the mechanism of action of thiourea and related compounds; inhibition of oxidative enzymes ...
Moreover, the binding energies corresponding to the same ligands and calculated for both tyrosinase and tyrosine hydroxylase are also correlated with each other, suggesting that tyrosinase inhibitors may also have an inhibitory effect on tyrosine hydroxylase. Compounds 3j and 3k have also very strong ...
Vrana, Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase, J. Neurosci. Res. 54 (1998) 691 A/697.Y. Xu, A.H. Stokes, R. Roskoski Jr., K.E. Vrana, Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine ...
Winder AJ, Harris H (1991) New assay for the tyrosinase hydroxylase and dopa oxidase activities of tyrosinase. Eur J Biochem 198:317–321 View ArticleWinder J, Harris H (1991) New assays for tyrosine hydroxylase and dopa oxidase activities of tyrosinase. Eur J Biochem 198:317–326...
Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase. J Neurochem Res. 1998:691-697.Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase. Y Xu,AH Stokes,RJ Roskoski,KE Vrana. Journal of Neuroscience Research ...
1994. Nonlinkage of bipolar illness to tyrosine hydroxylase, tyrosinase, and D2 and D4 dopamine receptor genes on chromosome 11. Am J Psychiatry 151:102±106.Debruyn A, Mendelbaum K, Sandkuijl L, Delvenne V, Hirsch D, Staner L, Mendlewicz J, Van Broeckhoven C. 1994. Nonlinkage of ...
The melanosomal membrane isoform-I of tyrosine hydroxylase (referred to hereafter as THI) converts the L-tyrosine substrate to the L-DOPA intermediate product, and this step stimulates tyrosinase enzyme activation. The cytosolic enzyme form phenylalanine hydroxylase (PAH) converts L-phenylalanine residu...