Mattson MP. Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle. NPJ Aging Mech Dis 2015;1.Mattson MP. Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle. Nat Aging Mech Dis. 2015;1:15003....
Mutations in the genes encoding α-synuclein and glucocerebrosidase can cause rare cases of LBD.18 Up to 75% of PD patients will develop clinical dementia, which typically occurs after the onset of autonomic and motor symptoms. Compared with age-matched control subjects, and dementia-free PD ...
About 5–10 per cent of the population over 65 has some kind of cognitive decline which is considered to be abnormal for this age group. Among these, more than 50 per cent will have a dementia of degenerative aetiology, of which the most common is Alzheimer's disease (AD). However, ...
Atypical and early-onset dementias can be particularly problematic for family caregivers, and support groups aimed at memory loss and Alzheimer's disease a... Megan,E,O'Connell,... - 《Dementia》 被引量: 28发表: 2014年 Family Caregivers of Individuals with Intellectual Disability: Perspectives ...
Although the criteria for the diagnosis of dementia demand multiple domains of cognitive impairment, isolated deficits such as amnesia, dyslexia or dysphasia may be the early manifestations of a dementing process. For example, early language disorder, although unusual in AD, may be the presentation ...
Conclusions Individuals with DS demonstrated a unique pattern of age-related effects on gray matter and ventricular volume, the latter of which was associated with dementia rating scores in the DS group. Results may indicate that early onset of brain aging in DS is primarily due to DS-specific ...
Slattery C, Beck JA, Harper L, Adamson G, Abdi Z, Uphill J, et al. R47H TREM2 variants increases risk of typical early-onset Alz- heimer's disease but not of prion or frontotemporal dementia. Alz- heimers Dement 2014;10:602-6084....
The presence of the apolipoprotein E (APOE) ε4 allele is a definite risk factor for the onset of Alzheimer’s disease (AD). Its presence seems... C Marra,A Bizzarro,A Daniele,... - 《Dementia & Geriatric Cognitive Disorders》 被引量: 149发表: 2004年 Synthesis and amyloid binding prop...
R47H TREM2 variants increases risk of typical early-onset Alz- heimer's disease but not of prion or frontotemporal dementia. Alz- heimers Dement 2014;10:602-6084.Slattery CF, Beck JA, Harper L, Adamson G,Abdi Z, Uphill J, et al. R47H TREM2 variant increases risk of typical early-...
For example, aphasia was diagnosed to be associated with disorders of consciousness or dementia. This is also reflected in the calculated CI values. Diagnostic accuracy was not influenced by factors such as age, gender, place of residence and the hospital that the patient was transported to. The...