The injectable Vi polysaccharide typhoid vaccine is cheap (50 US cents per dose) and potentially useful in developing countries. There have been questions, however, about programme feasibility, whether it is protective in young children (aged 2–5 years), and whether it is ableBMJ...
Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of Salmonella Typhi: a randomised controlled, phase 2b trial. Lancet 390, 2472–2480 (2017). Article CAS PubMed PubMed Central Google Scholar Meiring,...
Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of Salmonella Typhi: a randomised controlled, phase 2b trial. Lancet 390, 2472–2480 (2017). Article CAS PubMed PubMed Central Google Scholar Meiring,...
Inequality in the immunization schedules of different states of the Same Country: Are we aware? Bharat Biotech, which has rolled out a live attenuated oral rotavirus vaccine in India, announced results from a study using its Typbar TCV, a conjugated typhoid vaccine, in The Lancet. India is an...
A cluster-randomized effectiveness trial of Vi typhoid vaccine in India. BACKGROUND: Typhoid fever remains an important cause of illness and death in the developing world. Uncertainties about the protective effect of Vi polysacc... D Sur,RL Ochiai,SK Bhattacharya,... - 《N Engl J Med》 被...
An exception is Typbar typhoid conjugate vaccine produced by Bharat Biotech in India, which is licensed Sample size Since the underlying vaccine preventable disease incidence will not be known a priori, conceptually, the sample size for a probe study can be approached by identifying the level of ...
Vaccination, which requires strict planning and proper targeting of the vulnerable age groups, is considered to be an effective tool in controlling this disease in endemic areas, given there is development of a conjugate vaccine against both serovars (S. Typhi and S. Para A). 展开 ...
DPT vaccine- abbreviation for combination vaccine against diphtheria and pertussis (whooping cough) and tetanus toxoids; usually given in a series of injections in early childhood immunizing agent,immunogen- any substance or organism that provokes an immune response (produces immunity) when introduced ...
A cluster-randomized effectiveness trial of Vi typhoid vaccine in India. N Engl J Med. 361, 335–344 (2009). Article CAS PubMed Google Scholar Haghjoo, E. & Galán, J. E. Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-...
Safety and Immunogenicity of Vi Conjugate Vaccines for Typhoid Fever in Adults, Teenagers, and 2- to 4-Year-Old Children in Vietnam The capsular polysaccharide of Salmonella typhi, Vi, is an essential virulence factor and a protective vaccine for people older than 5 years. The safety an... ...