What are transcription factors? This lesson will define transcription factors, discuss their functions, and their unique classes.
46 -- 20:37 App 【转录因子】Transcription Factors Part 5 103 -- 51:08 App Optic Gliomas in NF1 - 神经纤维瘤病1型 视神经胶质瘤 59 -- 8:09 App Trauma of the Anterior Segment Part 1-眼外伤:眼前节部分 293 -- 26:42 App 【钙粘蛋白】Cadherins Part 1 67 -- 18:11 App DNA...
DNase1 footprint analysis showed the α-Amy2/A promoter to be a complex array of binding sites for a number of different classes of DNA-binding proteins. Our data suggest that the area around the initiator element (Inr) is bound by a large complex of general transcription factors, that ...
Transcription factor, molecule that controls the activity of a gene by determining whether the gene’s DNA is transcribed into RNA. Transcription factors control when, where, and how efficiently RNA polymerases, which catalyze the reactions that synthesi
Transcription Factors (TFs), essential for many cellular processes, generally work coordinately to induce transcriptional change in response to internal and external signals. Disrupted cooperation between TFs, leading to dysregulation of target genes, contributes to the pathogenesis of many diseases, ...
We propose an evolutionary definition of a cell type that allows cell types to be delineated and compared within and between species. Key to cell type identity are evolutionary changes in the 'core regulatory complex' (CoRC) of transcription factors, that make emergent sister cell types distinct,...
The expression of genes required for progression through the cell cycle is highly modulated through a regulatory axis containing the E2F transcription fact... MJJ Watson - 《Cellular & Molecular Life Sciences》 被引量: 116发表: 2003年 Identification of transcription factors involved in root apex res...
In addition, we analyzed the soma size distribution and percentage contribution of each cell type in the DRG using in situ hybridization data (Fig. 4b, c). Finally, we interrogated each of the neuron types for unique expression patterns for transcription factors, ion channels, G-protein couple...
Existing induction methods, however, mostly rely on the effects of the combined action of multiple added growth factors, which generally tend to result in mixed populations of neurons. Here, we report that overexpression of specific transcription factors (TFs) in ESCs can rather guide the ...
Disease typically arises from the insertion of transposons into particular regions of genes that are involved in regulating gene activity. For example, insertions near promoter regions, which are short segments of DNA that are used to initiate gene transcription (the synthesis of RNA from DNA), ...