reported using enzymes instead of fluorescein-labeled antibodies to develop the enzyme-labeled antibody approach (Enzyme-labeled antibody technique) for the localization and identification of antigens in biological tissues, respectively. Engvall Van Weemen et al. published the enzyme-labeled immunosorbent ...
c, Cluster heat map of Spearman correlations of the cell type basis matrix column space derived from Tabula Sapiens. Color bar denotes correlation value. d, Mean fractional contributions of cell-type-specific RNA in the plasma cell-free transcriptome (n = 18 patients). e, Top tissues in...
In this study, we characterized resident cell-types, ECM composition and ultrastructure in relation to microanatomy of the ONH in adult domestic cats (Felis catus). Longitudinal and transverse cryosections of ONH tissues were immunolabeled with astrocyte, microglia/macrophage, oligodendrocyte, LC ...
Connective tissue forms the structural support of living things, especially vertebrates. Tissues meeting this definition serve a variety of functions throughout the body, and the building blocks of many of these connective tissues are collagen fibers. Collagen is a protein – in fact, it is the m...
with subsequent labelling on the basis of the expression of known marker genes. The comprehensive list of tissues and cell types, along with their annotations, can be found at the Human Cell Atlas (http://catlas.org/humanenhancer/#!/cellType). The original atlas included 222 fetal and adult...
The lamprey, a primitive jawless vertebrate whose ancestors diverged from all other vertebrates over 500 million years ago, offers a unique window into the ancient formation of the retina. Using single-cell RNA-sequencing, we characterize retinal cell types in the lamprey and compare them to those...
Advances in high-throughput single-cell RNA sequencing (scRNA-seq) and single-nucleus RNA sequencing (snRNA-seq) have enabled related activity focused on determining the extent to which cell types, the functional units of complex tissues6,7, are conserved among species. Analysing patterns of cell...
Fresh-frozen (FF) or formalin-fixed paraffin-embedded (FFPE) sample tissues obtained through biopsy or excision of the malignant mass for staining or immunohistochemical analysis FF or FFPE tissue specimens for profiling through molecular, biochemical, proteomic, and metabolic studies Urine and whole...
Since the thyroid gland is controlled by the pituitary gland and hypothalamus, disorders of these tissues can also affect thyroid function and cause thyroid problems. What are the specific kinds of thyroid disorders? There are specific kinds of thyroid disorders that include: Hypothyroidism Hyperthyroidi...
Cell therapy has emerged as a viable approach for treating damaged organs or tissues, particularly with advancements in stem cell research and regenerative medicine. The innovative technique of cell sheet engineering offers the potential to create a cell-dense lamellar structure that preserves the extrac...