Progressive supranuclear palsyProgressive supranuclear palsy, or PSP, is a neurological disorder that can be characterized by some of the same symptoms seen in Parkinson’s disease, like rigidity, cognitive changes, and sleep problems. However, people with PSP tend to have additional symptoms, like ...
Forms of atypical parkinsonism that have been associated with neurocognitive disorder include progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy, and vascular parkinsonism. Neurocognitive disorder with Lewy bodies is often included in this group of atypical parkinsonian syndromes ...
Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by the progressive accumulation of amyloid-beta and neurofibrillary tangles of tau in the neocortex. We profiled DNA methylation in two regions of the cortex from 631 donors, performing an epigenome-wide association study o...
Progressive supranuclear palsyFreezing of gait (FOG) is an episodic gait pattern that is common in advanced Parkinson's disease (PD) and other atypical parkinsonism syndromes. Recently, disturbances in the pedunculopontine nucleus (PPN) and its connections have been suggested to play a critical role...
[F-18]FDG demonstrate distinct patterns of decreased uptake for Alzheimer's disease (AD), Dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD) as well as its multiple subtypes such as behavioral variant FTD, primary progressive aphasia (PPA), progressive supranuclear palsy, and ...