f, DN B cells and subsets; ratio of DN2:DN1 expressed as log2 value. g, IgD- ASC and CD20−CD38hi PC. h, cTfh. SLE sub-group frequency of each population is compared to the HD group for statistical significance
The opposite of the significance level, calculated as 1 minus the significance level, is the confidence level. It indicates the degree of confidence that the statistical result did not occur by chance or by sampling error. The customaryconfidencelevel in many statistical tests is 95%, leading to...
. GET also accurately predicted expression log fold change between two cell types, even when one of them was unseen (Extended Data Fig.2b). Across a wide range of fetal cell types evaluated, GET consistently outperformed genome-wide prediction using Enformer’s cap analysis of gene expression (...
Types of Chi-Square Test How to Perform a Chi-Square Test Example of a Chi-Square Test When Should You Use the Chi-Square Test? Properties of the Chi-Square Test Limitations of the Chi-Square Test Conclusion FAQs What is a Chi-Square Test? The Chi-Square test is a statistical hypoth...
The type of statistical test performed depended on the results from Normality and Lognormality tests (Shapiro-Wilk, Kolmogorov-Smirnov) were passed is indicated in the respective figure legend Quantification of ciliary beating We aligned all light-transmission brain ventricle recordings using a custom-...
For general statistical analysis we used a Mann–Whitney U-test. For the cumulative density function analysis in Fig. 4j we used a two-sample Kolmogorov–Smirnov test. For both tests, ns indicates p ≥ 0.05 and significance is *p < 0.05, **p < 0.01, ***p < 0.001 ...
For GSEA, we adopted permutation tests (1,000 times) to generate a normalized enrichment score (NES) for each candidate pathway. A hierarchical clustering on the expression levels of the Reactome pentose phosphate pathway (15 genes total, of which two genes were removed due to high-frequency ...
Pre-operative memory function tests were carried out as part of the routine clinical assessment as previously described [44] and detailed in Additional file 2: Methods. Data on memory function was available in 15 adult surgical pa- tients (Additional file 1: Table S1). Statistical analysis was...
Astrocytes, which can be further divided intoprotoplasmicandfibroustypes, can sense the level of glucose and ions such as potassium in the brain and thereby regulate the flux of these molecules across the blood-brain barrier. The sheer abundance of these cells makes them a major source of basic...
Two-tailed student t tests were used for all statistical comparisons. Error bars in Fig. 4c, d, f indicate the standard error of the mean of three independent biological replicates (n = 3). Full size image We next designed two sgRNAs targeting rs58415480 and measured the expression of...