evaluation of the neurological status of the acutely injured pediatric patient can be problematic, especially the GCS. Some prefer to use the AVPU system (Alert, Responds to Verbal, Responds to Pain, and Unresponsive). Due to the disproportionately...
Discrete subicular circuits control generalization of hippocampal seizures 2022, Nature Communications Cellular resolution anatomical and molecular atlases for prenatal human brains 2022, Journal of Comparative Neurology Noncanonical projections to the hippocampal CA3 regulate spatial learning and memory by modulati...
Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease characterized by clusters of blood-filled capillary spaces lined by “leaky” endothelium [1,2]. CCM patients present with highly variable symptomatology, including seizures, hemorrhagic activity, and focal neurologic deficits [2]...
Acute treatment Systemic hives Antihistamines Second organ involved in an acute-onset reaction (upper/lower airway, GI, neurological, CV) Must be associated: Acute onset of: Hypotension Laryngeal edema O2 desaturation Seizures Epinephrine intramuscular can repeat ×3 q 5–15 minutes Complementary ...
Types of Disasters Paul N. Severin and Phillip A. Jacobson 5 5.1 Unique Vulnerabilities of Children Although pediatric patients are viewed as a unique population, they are the popula- tion: it has been estimated that more than 25% of the U.S. population fits within the ...
can cause sudden loss of consciousness in some patients, while comas caused by metabolic abnormalities orcerebraltumoursare characterized by a more gradual onset, with stages of lethargy and stupor before true coma.Metabolic comas are also more likely to have associated brain seizures and usually le...
Intrahippocampal infusion of botulinum neurotoxin E (BoNT/E) reduces spontaneous recurrent seizures in a mouse model of mesial temporal lobe epilepsy. Epilepsia 2009, 50, 963–966. 120. Costantin, L.; Bozzi, Y.; Richichi, C.; Viegi, A.; Antonucci, F.; Funicello, M.; Gobbi, M.; ...