What is a trial with Wennberg's design?Our musingsReferencesdoi:10.1002/9780470691922.ch2Alejandro R. JadadMurray W. EnkinJohn Wiley & Sons, LtdJadad A: Types of randomized controlled tri- als. In: Randomized Controlled Trials. Jadad A (Ed). London, BMJ Books, 1998, pp 10 -27...
extended-release levetiracetam as adjunctive treatment of partial-onset seizures in patients with epilepsy: a double-blind, randomized, placebo-controlled trial... J Peltola,C Coetzee,F Jiménez,... - 《Epilepsia》 被引量: 108发表: 2010年 Meta-Analysis of Randomized Trials on First Line and Adj...
We systematically searched PubMed, Embase, and the Cochrane databases for meta-analyses of randomized controlled trials (RCTs) investigating the association between IF and metabolic health outcomes. Subsequently, we performed an umbrella review and network meta-analysis (NMA) to evaluate the efficacy o...
while whole fruit is probably a better option, fruit juice does not seem to have any clear negative effects. For example, a systematic review and meta-analysis of randomized controlled trials demonstrated that fruit juice had an overall neutral impact on blood sugar levels (20). ...
Low–Glycemic Index Diets in the Management of Diabetes A meta-analysis of randomized controlled trials Diabetes Care Livesey G et al, 2008, Glycemic response and health—a systematic review and meta-analysis: relations between dietary glycemic properties and health outcomes The American Journal of ...
Randomized controlled trials (RCTs) are conducted when exploring causal association, but they face issues such as high cost, complexity, and human ethics [11]. Traditional observational studies cannot exclude confounding factors that interfere with the results. Therefore, Mendelian randomization (MR) be...
However, several studies have found no benefit of vitamin E in preventing lung and breast cancers. More randomized controlled trials are needed to determine the effect of vitamin E on cancer risks. Alzheimer's disease is a degenerative brain disease with progressive loss of mental capacity, ...
Combined physical and cognitive training for older adults with and without cognitive impairment: a systematic review and network meta-analysis of randomized controlled trials. Ageing Res Rev. 2021;66:101232. doi:10.1016/j.arr.2020.101232 PubMedGoogle ScholarCrossref 23. O’Keefe JH,...
A systematic review and meta-analysis of randomized controlled trials published in 2022 by Abbas et al. [6] assessed the beneficial and adverse effects of nusinersen. The findings demonstrated a significant risk difference in motor milestone response (0·51, 95% CI: 0·39, 0·62) and improvem...
Learn more aboutRandomized Controlled TrialsandRandom Assignment in Experiments. Randomized Block Designs Nuisance factors are variables that can affect the outcome, but they are not the researcher’s primary interest. Unfortunately, they can hide or distort the treatment results. When experimenters know...