CONCLUSIONS Two types of prostate cancer cells, CD57+ and CD44+, were identified. The finding that most primary tumors contain a predominantly CD57+ cancer cell population agrees with the argument that cancer cells arise from the transformation of CD57+ luminal cells. However, CD44+ cancer ...
Prostate cancer, like other malignancies, arise when genetic alterations in the prostate gland cells cause uncontrolled division of abnormal cells. These tumors (primary) invade the surrounding healthy tissue, destroying it and spreading further. Eventually the cancerous cells may infiltrate surrounding or...
The cancer cell types included prostate cancer cell lines LNCaP, C4-2, CL1, PC3, DU145, tumor xenografts LuCaP 35 and LuCaP 49, CD26+ Gleason pattern 3 (G3) and pattern 4 (G4) cancer cells isolated from primary tumors [8]. G3 cancer cells are typical of well-differentiated tumors...
and Propose Prognostic Subtypes Jahanshah Ashkani1,2 & Kevin J. Naidoo1,2 Aberrant glycosylation in tumours stem from altered glycosyltransferase (GT) gene expression but can the expression profiles of these signature genes be used to classify cancer types and lead to cancer subtype ...
Northstar enables automatic classification of known and novel cell types from tumor samples Article Open access 17 September 2020 Cell type matching in single-cell RNA-sequencing data using FR-Match Article Open access 15 June 2022 Pan-cancer classification of single cells in the tumour microen...
Skin cancer, the abnormal growth of cells in the skin, is the most common type of cancer. It’s almost always cured when it’s found early and treated, so it’s important to see your doctor if you have changes in your skin. Learn More Lung Cancer Lung cancer is the leading cause...
The type of cancer is named for the type of cell from which it forms. For example, carcinoma (from epithelial cells), sarcoma (formed in bone and soft tissues), leukemia (blood tissue), lymphoma (formed in B or T lymphocytes), multiple Myeloma (plasma cells, myeloma cells), and ...
Expertise in mesothelioma, cancer therapy and immunotherapy Licensed and registered nurse Graduated from University of South Alabama (B.S.), University of Central Florida (M.B.A) Member of the Academy of Oncology Nurse & Patient Navigators
For example, prostate cancer may cause elevated levels of prostate-specific antigen, or PSA, in the blood-stream. Products for different tumor types Solid tumors are heterotypic aggregates of many cell types, including cancer cells, cancer stem cells, connective-tissue cells, and immune cells. ...
Transcriptional heterogeneity among malignant cells of a tumor has been studied in individual cancer types and shown to be organized into cancer cell states; however, it remains unclear to what extent these states span tumor types, constituting general features of cancer. Here, we perform a pan-ca...