In recent decades, cultivation-independent genomics has greatly increased our knowledge of natural microbial diversity [1,2,3]. This has led to the discovery of many new major lineages, including phyla and superphyla, such as the DPANN archaea, and to the redrawing of the Tree of Life [1,4...
In recent decades, cultivation-independent genomics has greatly increased our knowledge of natural microbial diversity [1,2,3]. This has led to the discovery of many new major lineages, including phyla and superphyla, such as the DPANN archaea, and to the redrawing of the Tree of Life [1,4...
With a machine learning pipeline of feature selection, dimension reduction, clustering, and classification we identified three AM biotypes鈥攎ild, comorbid, and moderate AM biotypes (MIA, COA, and MOA)鈥攆rom a Human Connectome Project (HCP) discovery sample (194 drinkers). The three groups ...
This step was carried out using the standard robust multi-array average (RMA) method [25], implemented in the analysis pipeline SBEAMS [26]. The strength of differential expression between any pair of experiments was estimated by M i = log2(ratio) = X i -X a , where a represented one...
Copy number estimation Broad Institute http://archive.broadinstitute.org/cancer/cga/copynumber_pipeline Significant focal copy number change – GISTIC 2.0 Mermel et al., 2011 http://software.broadinstitute.org/software/cprg/?q=node/31 Purity, ploidy, genome doubling - ABSOLUTE Carter et al., ...
varied among biotypes; trehalase,β-N-acetylglucosaminidase (chitinase), two separate glucose dehydrogenases, calreticulin, aminopeptidase, acetylglucosaminyltransferase, hydroxymethylglutaryl-CoA lyase, acyltransferase, ficolin-3, lava lamp, retinaldehyde-binding protein, and two proteins of unknown function....
In this study, several machine learning algorithms, described in Section 2.2, Section 2.3, Section 2.4 and Section 2.5, were integrated to analyze the gene expression profiling data of four cell types with three smoking statuses. The data on each cell type were analyzed in the same pipeline. ...
Therefore, the management of the R&D pipeline and the securing of IP rights are core elements of the business. Hence, we note this the industry has been adopting and utilizing OI faster than any other industry. The OI activities that occur between companies are seen as contractual records, ...