The patent application cannot be based on a speculative use or a possible future use. This is one of the easier requirements for a patent application to meet. While it must describe how the invention will achieve one or more goals, the invention doesn’t necessarily have to achieve that ...
Cell-free RNA from liquid biopsies can be analyzed to determine disease tissue of origin. We extend this concept to identify cell types of origin using the Tabula Sapiens transcriptomic cell atlas as well as individual tissue transcriptomic cell atlases
The California Institute of Technology has filed and licensed a patent application for the work described in this manuscript with S.R.K., B.E.D., and V.G. listed as inventors (Caltech disclosure reference no. CIT 8198). Additional information ...
In the United States alone, the disability due to depression exacts an annual cost of $236 billion (6). The burden of depression has the greatest impact on young people, and the consequences are fatal all too often. Death by suicide has tripled in young people over the past decade (7)...
2015-1812 (Fed. Cir. Nov. 21, 2016), that the Patent Trial and Appeal Board’s application of the statute and the PTO’s regulation were too broad. Under that broader application, the Board noted that the subject matter of the claims was “incidental or complementary to” potential sales...
Engineering disease-resistant plants can be a powerful solution to the issue of food security. However, it requires addressing two fundamental questions: what genes to express and how to control their expressions. To find a solution, we screen CRISPR-edited upstream open reading frame (uORF) varia...
R.M.S., T.A.C. and L.G.T.M. are inventors on a provisional patent application (62/569,053) filed by Memorial Sloan Kettering (MSK) relating to the use of TMB in cancer immunotherapy. M.D.H., N.A.R. and T.A.C. are inventors on a PCT patent application (PCT/US2015/062208...
U.S. Patent Application Ser. No. 09/778,444, Filed Feb. 7, 2001, " Systems and Methods for Low-Loss Splicing of Optical Fibers Having A High Concentration of Fluorine to Other Types of Optical Fiber, " Riis.US6565269 Feb 7, 2001 May 20, 2003 Fitel Usa Corp. Systems and methods ...
A.T. and G.F. are inventors of two US Provisional patent applications (62/860,952 and 62/851,205) that describe the methods in this paper. Additional information Peer reviewer informationNature Methodsthanks the anonymous reviewers for their contribution to the peer review of this work. Lei ...
United States Patent 8615367 Abstract: Disclosed is number coding of pairs (“doublets”) or small sets (“multiplets”) of solid phase carriers which provides distinguishable subtypes of a given type of such carriers, where each carrier type is distinguishable on the bases of a different code. ...