Curnow SJ, Fairclough M, Schmutz C, Kissane S, Denniston AK, et al. (2010) Distinct types of fibrocyte can differentiate from mononuclear cells in the presence and absence of serum. PloS one 5: e9730.Curnow SJ, Fairclough M, Schmutz C, et al. Distinct types of fibrocyte can ...
Weber C, Schober A, Zernecke A (2004) Chemokines: key regulators of mononuclear cell recruitment in atherosclerotic vascular disease. Arterioscler Thromb Vasc Biol 24(11):1997–2008 CAS PubMed Google Scholar Davidson SM, Duchen MR (2007) Endothelial mitochondria: contributing to vascular function ...
The initial step in analyzing single-cell data typically involves annotating cells based on their known and novel cell types. One commonly used strategy, known as “cluster-then-annotate,” involves grouping cells into clusters based on the similarity of their gene expression profiles and manually c...
PBMCs, peripheral blood mononuclear cells. Download:Download high-res image (1MB) Download:Download full-size image Figure 4. Evaluation of scCATCH (A) Cell types were annotated via scCATCH in three internal and three external datasets. Cluster numbers are provided with the corresponding cells. Cel...
Thymidine kinase (TK) isoenzymes and thymidine phosphorylase (TP) activities have been measured in peripheral mononuclear cells of patients with acute lymphoblastic and monoblastic leukaemia or B-chronic lymphocytic leukaemia, as well as in normal subjects, and also in lymph node cells from patients ...
(MG), a neurological autoimmune condition, manifests as debilitating muscle weakness resulting from autoantibodies targeting acetylcholine receptors (AChRs). For the purpose of investigating the immune dysregulation in early-onset AChR+ MG, we performed a detailed analysis of peripheral mononuclear blood ...
Monocytes are agranulocytes that are the largest of all white blood cells, some of which also act as precursor cells of macrophages, osteoclasts, microglia, and other cells of the mononuclear phagocyte system in connective tissue. Circulating monocytes have diameters of 12-15 μm, but macrophages...
In the 26-dataset, PBMC was annotated as peripheral blood mononuclear cell (CL:2000001). This cell type is not part of Tabula Muris Senis (because blood is not on the tissues in the atlas), but many of its descendants were in TMS. As a result, we excluded this cell type in our ...
Adult neurogenesis, fundamental for cellular homeostasis in the mammalian olfactory epithelium, requires major shifts in gene expression to produce mature olfactory sensory neurons (OSNs) from multipotent progenitor cells. To understand these dynamic eve
Type 1 immunity consists of T-bet(+) IFN-γ-producing group 1 ILCs (ILC1 and natural killer cells), CD8(+) cytotoxic T cells (TC1), and CD4(+) TH1 cells, which protect against intracellular microbes through activation of mononuclear phagocytes. Type 2 immunity consists of GATA-3(+) ...